Delayed-onset ataxia in mice lacking α-tocopherol transfer protein: model for neuronal degeneration caused by chronic oxidative stress T Yokota, K Igarashi, T Uchihara, K Jishage, H Tomita, A Inaba, Y Li, ... Proceedings of the National Academy of Sciences 98 (26), 15185-15190, 2001 | 288 | 2001 |
HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin FKY 23. Morita M, Ohneda O, Yamashita T, Takahashi S, Suzuki N, Nakajima O ... EMBO J 22 (5), 1134-46, 0 | 286* | |
Molecular determinants differentiating photocurrent properties of two channelrhodopsins from chlamydomonas H Wang, Y Sugiyama, T Hikima, E Sugano, H Tomita, T Takahashi, ... Journal of Biological Chemistry 284 (9), 5685-5696, 2009 | 225 | 2009 |
Channelrhodopsin-2 gene transduced into retinal ganglion cells restores functional vision in genetically blind rats H Tomita, E Sugano, H Isago, T Hiroi, Z Wang, E Ohta, M Tamai Experimental eye research 90 (3), 429-436, 2010 | 175 | 2010 |
Involvement of Inflammation, Degradation, and Apoptosis in a Mouse Model of Glaucoma*♦ X Zhou, F Li, L Kong, H Tomita, C Li, W Cao Journal of Biological Chemistry 280 (35), 31240-31248, 2005 | 173 | 2005 |
Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter H Tomita, E Sugano, Y Fukazawa, H Isago, Y Sugiyama, T Hiroi, ... PloS one 4 (11), e7679, 2009 | 159 | 2009 |
Restoration of visual response in aged dystrophic RCS rats using AAV-mediated channelopsin-2 gene transfer H Tomita, E Sugano, H Yawo, T Ishizuka, H Isago, S Narikawa, S Kügler, ... Investigative ophthalmology & visual science 48 (8), 3821-3826, 2007 | 158 | 2007 |
Near-infrared (NIR) up-conversion optogenetics S Hososhima, H Yuasa, T Ishizuka, MR Hoque, T Yamashita, ... Scientific reports 5 (1), 16533, 2015 | 127 | 2015 |
Retinal ganglion cell protection by 17‐β‐estradiol in a mouse model of inherited glaucoma X Zhou, F Li, J Ge, SR Sarkisian Jr, H Tomita, A Zaharia, J Chodosh, ... Developmental neurobiology 67 (5), 603-616, 2007 | 104 | 2007 |
Optogenetically induced seizure and the longitudinal hippocampal network dynamics S Osawa, M Iwasaki, R Hosaka, Y Matsuzaka, H Tomita, T Ishizuka, ... PloS one 8 (4), e60928, 2013 | 100 | 2013 |
Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death G Li, RE Anderson, H Tomita, R Adler, X Liu, DJ Zack, RVS Rajala Journal of Neuroscience 27 (1), 203-211, 2007 | 93 | 2007 |
Characteristics of mitochondrial calpains T Ozaki, H Tomita, M Tamai, S Ishiguro Journal of biochemistry 142 (3), 365-376, 2007 | 92 | 2007 |
Intrinsic activation of PI3K/Akt signaling pathway and its neuroprotective effect against retinal injury T Nakazawa, M Shimura, H Tomita, H Akiyama, Y Yoshioka, H Kudou, ... Current eye research 26 (1), 55-63, 2003 | 87 | 2003 |
Mechanism of protection from light-induced retinal degeneration by the synthetic antioxidant phenyl-N-tert-butylnitrone H Tomita, Y Kotake, RE Anderson Investigative ophthalmology & visual science 46 (2), 427-434, 2005 | 83 | 2005 |
Dissecting a role for melanopsin in behavioural light aversion reveals a response independent of conventional photoreception M Semo, C Gias, A Ahmado, E Sugano, AE Allen, JM Lawrence, H Tomita, ... PloS one 5 (11), e15009, 2010 | 80 | 2010 |
Auto iris pigment epithelial cell transplantation in patients with age-related macular degeneration: short-term results T Abe, M Yoshida, H Tomita, T Kano, M Sato, Y Wada, N Fuse, T Yamada, ... The Tohoku journal of experimental medicine 191 (1), 7-20, 2000 | 78 | 2000 |
Protective effect against ischemia and light damage of iris pigment epithelial cells transfected with the BDNF gene T Kano, T Abe, H Tomita, T Sakata, S Ishiguro, M Tamai Investigative ophthalmology & visual science 43 (12), 3744-3753, 2002 | 68 | 2002 |
Presence of mitogen-activated protein kinase in retinal Müller cells and its neuroprotective effect ischemia–reperfusion injury H Akiyama, T Nakazawa, M Shimura, H Tomita, M Tamai Neuroreport 13 (16), 2103-2107, 2002 | 66 | 2002 |
Neuroprotective effect of nipradilol on axotomized rat retinal ganglion cells T Nakazawa, H Tomita, K Yamaguchi, Y Sato, M Shimura, S Kuwahara, ... Current eye research 24 (2), 114-122, 2002 | 65 | 2002 |
Immune responses to adeno-associated virus type 2 encoding channelrhodopsin-2 in a genetically blind rat model for gene therapy E Sugano, H Isago, Z Wang, N Murayama, M Tamai, H Tomita Gene therapy 18 (3), 266-274, 2011 | 62 | 2011 |