John Connelly
John Connelly
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Extracellular-matrix tethering regulates stem-cell fate
B Trappmann, JE Gautrot, JT Connelly, DGT Strange, Y Li, ML Oyen, ...
Nature materials 11 (7), 642-649, 2012
Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions
JT Connelly, JE Gautrot, B Trappmann, DWM Tan, G Donati, WTS Huck, ...
Nature cell biology 12 (7), 711-718, 2010
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers
OMT Pearce, RM Delaine-Smith, E Maniati, S Nichols, J Wang, S Böhm, ...
Cancer discovery 8 (3), 304-319, 2018
Inhibition of in vitro chondrogenesis in RGD-modified three-dimensional alginate gels
JT Connelly, AJ García, ME Levenston
Biomaterials 28 (6), 1071-1083, 2007
Dynamic compression regulates the expression and synthesis of chondrocyte-specific matrix molecules in bone marrow stromal cells
JK Mouw, JT Connelly, CG Wilson, KE Michael, ME Levenston
Stem cells 25 (3), 655-663, 2007
Exploiting the superior protein resistance of polymer brushes to control single cell adhesion and polarisation at the micron scale
JE Gautrot, B Trappmann, F Oceguera-Yanez, J Connelly, X He, FM Watt, ...
biomaterials 31 (18), 5030-5041, 2010
Interactions between integrin ligand density and cytoskeletal integrity regulate BMSC chondrogenesis
JT Connelly, AJ García, ME Levenston
Journal of cellular physiology 217 (1), 145-154, 2008
Type VI collagen regulates dermal matrix assembly and fibroblast motility
G Theocharidis, Z Drymoussi, AP Kao, AH Barber, DA Lee, KM Braun, ...
Journal of investigative dermatology 136 (1), 74-83, 2016
Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells
RJ McMurray, AKT Wann, CL Thompson, JT Connelly, MM Knight
Scientific reports 3 (1), 3545, 2013
Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells
DWM Tan, KB Jensen, MWB Trotter, JT Connelly, S Broad, FM Watt
Development 140 (7), 1433-1444, 2013
Tensile loading modulates bone marrow stromal cell differentiation and the development of engineered fibrocartilage constructs
JT Connelly, EJ Vanderploeg, JK Mouw, CG Wilson, ME Levenston
Tissue Engineering Part A 16 (6), 1913-1923, 2010
Characterization of proteoglycan production and processing by chondrocytes and BMSCs in tissue engineered constructs
JT Connelly, CG Wilson, ME Levenston
Osteoarthritis and cartilage 16 (9), 1092-1100, 2008
Clonal growth of dermal papilla cells in hydrogels reveals intrinsic differences between Sox2-positive and-negative cells in vitro and in vivo
RR Driskell, VR Juneja, JT Connelly, K Kretzschmar, DWM Tan, FM Watt
Journal of Investigative Dermatology 132 (4), 1084-1093, 2012
Adipogenic differentiation of hMSCs is mediated by recruitment of IGF‐1r onto the primary cilium associated with cilia elongation
MT Dalbay, SD Thorpe, JT Connelly, JP Chapple, MM Knight
Stem Cells 33 (6), 1952-1961, 2015
Tissue stiffening promotes keratinocyte proliferation through activation of epidermal growth factor signaling
FN Kenny, Z Drymoussi, R Delaine-Smith, AP Kao, AC Laly, MM Knight, ...
Journal of cell science 131 (10), jcs215780, 2018
Integrin-mediated adhesion and mechano-sensing in cutaneous wound healing
FN Kenny, JT Connelly
Cell and tissue research 360, 571-582, 2015
The influence of cyclic tension amplitude on chondrocyte matrix synthesis: experimental and finite element analyses
JT Connelly, EJ Vanderploeg, ME Levenston
Biorheology 41 (3-4), 377-387, 2004
Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation
JT Connelly, A Mishra, JE Gautrot, FM Watt
PloS one 6 (11), e27259, 2011
Fibronectin-and collagen-mimetic ligands regulate BMSC chondrogenesis in 3D hydrogels
JT Connelly, TA Petrie, AJ García, ME Levenston
European cells & materials 22, 168, 2011
The keratin network of intermediate filaments regulates keratinocyte rigidity sensing and nuclear mechanotransduction
AC Laly, K Sliogeryte, OJ Pundel, R Ross, MC Keeling, D Avisetti, ...
Science Advances 7 (5), eabd6187, 2021
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