Sabrina Spencer
Sabrina Spencer
University of Colorado-Boulder (Assistant Prof); Stanford University (Postdoc); MIT (PhD)
Verified email at - Homepage
Cited by
Cited by
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
SL Spencer, S Gaudet, JG Albeck, JM Burke, PK Sorger
Nature 459 (7245), 428-432, 2009
The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit
SL Spencer, SD Cappell, FC Tsai, KW Overton, CL Wang, T Meyer
Cell 155 (2), 369-383, 2013
Ki67 is a graded rather than a binary marker of proliferation versus quiescence
I Miller, M Min, C Yang, C Tian, S Gookin, D Carter, SL Spencer
Cell reports 24 (5), 1105-1112. e5, 2018
Measuring and modeling apoptosis in single cells
SL Spencer, PK Sorger
Cell 144 (6), 926-939, 2011
Modeling a snap-action, variable-delay switch controlling extrinsic cell death
JG Albeck, JM Burke, SL Spencer, DA Lauffenburger, PK Sorger
PLoS biology 6 (12), e299, 2008
Non-genetic cell-to-cell variability and the consequences for pharmacology
M Niepel, SL Spencer, PK Sorger
Current opinion in chemical biology 13 (5-6), 556-561, 2009
Irreversible APCCdh1 inactivation underlies the point of no return for cell-cycle entry
SD Cappell, M Chung, A Jaimovich, SL Spencer, T Meyer
Cell 166 (1), 167-180, 2016
Endogenous replication stress in mother cells leads to quiescence of daughter cells
M Arora, J Moser, H Phadke, AA Basha, SL Spencer
Cell reports 19 (7), 1351-1364, 2017
Synthesis: cancer research meets evolutionary biology
JW Pepper, C Scott Findlay, R Kassen, SL Spencer, CC Maley
Evolutionary applications 2 (1), 62-70, 2009
Modeling somatic evolution in tumorigenesis
SL Spencer, RA Gerety, KJ Pienta, S Forrest
PLoS computational biology 2 (8), e108, 2006
An ordinary differential equation model for the multistep transformation to cancer
SL Spencer, MJ Berryman, JA García, D Abbott
Journal of Theoretical Biology 231 (4), 515-524, 2004
Control of the Restriction Point by Rb and p21
J Moser, I Miller, D Carter, SL Spencer
Proceedings of the National Academy of Sciences 115 (35), E8219-E8227, 2018
A map of protein dynamics during cell-cycle progression and cell-cycle exit
S Gookin, M Min, H Phadke, M Chung, J Moser, I Miller, D Carter, ...
PLoS biology 15 (9), e2003268, 2017
Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states
KW Overton, SL Spencer, WL Noderer, T Meyer, CL Wang
Proceedings of the National Academy of Sciences 111 (41), E4386-E4393, 2014
Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis
S Gaudet, SL Spencer, WW Chen, PK Sorger
PLoS computational biology 8 (4), e1002482, 2012
Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes
DA Flusberg, J Roux, SL Spencer, PK Sorger
Molecular biology of the cell 24 (14), 2186-2200, 2013
Temporal integration of mitogen history in mother cells controls proliferation of daughter cells
M Min, Y Rong, C Tian, SL Spencer
Science 368 (6496), 1261-1265, 2020
Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways
M Min, SL Spencer
PLoS biology 17 (3), e3000178, 2019
Systematic calibration of a cell signaling network model
KA Kim, SL Spencer, JG Albeck, JM Burke, PK Sorger, S Gaudet, DH Kim
BMC bioinformatics 11 (1), 202, 2010
Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling
C Yang, C Tian, TE Hoffman, NK Jacobsen, SL Spencer
Nature Communications 12 (1), 1747, 2021
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