National Cancer Institute
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The architecture of the TIR domain signalosome in the Toll-like Receptor-4 signaling pathway
E Guven-Maiorov, O Keskin, A Gursoy, C VanWaes, Z Chen, CJ Tsai, ...
Scientific reports 5, 13128, 2015
The structural network of Interleukin-10 and its implications in inflammation and cancer
ES Acuner-Ozbabacan, BH Engin, E Guven-Maiorov, G Kuzu, ...
BMC genomics 15 (4), S2, 2014
The structural network of inflammation and cancer: merits and challenges
EG Maiorov, O Keskin, A Gursoy, R Nussinov
Seminars in cancer biology 23 (4), 243-251, 2013
A Structural View of Negative Regulation of the Toll-like Receptor-Mediated Inflammatory Pathway
E Guven-Maiorov, O Keskin, A Gursoy, R Nussinov
Biophysical journal 109 (6), 1214-1226, 2015
RACK1 is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy.
DG Secil Erbil, Ozlem Oral, Geraldine Mitou, Cenk Kig, Emel Durmaz-Timucin ...
Journal of Biological Chemistry, 2016
Structural host-microbiota interaction networks
E Guven-Maiorov, CJ Tsai, R Nussinov
PLoS computational biology 13 (10), e1005579, 2017
Pathogen mimicry of host protein-protein interfaces modulates immunity
E Guven-Maiorov, CJ Tsai, R Nussinov
Seminars in cell & developmental biology 58, 136-145, 2016
TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry
E Guven-Maiorov, O Keskin, A Gursoy, C VanWaes, Z Chen, CJ Tsai, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (11), 2646-2655, 2016
Prediction of Host–Pathogen Interactions for Helicobacter pylori by Interface Mimicry and Implications to Gastric Cancer
E Guven-Maiorov, CJ Tsai, B Ma, R Nussinov
Journal of Molecular Biology 429 (24), 3925-3941, 2017
Structural Pathways of Cytokines May Illuminate Their Roles in Regulation of Cancer Development and Immunotherapy
E Guven-Maiorov, SE Acuner-Ozbabacan, O Keskin, A Gursoy, ...
Cancers 6 (2), 663-683, 2014
Advances in template-based protein docking by utilizing interfaces towards completing structural interactome
S Muratcioglu, E Guven-Maiorov, ÷ Keskin, A Gursoy
Current opinion in structural biology 35, 87-92, 2015
Interface-Based Structural Prediction of Novel Host-Pathogen Interactions
E Guven-Maiorov, CJ Tsai, B Ma, R Nussinov
Computational Methods in Protein Evolution, 317-335, 2019
Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization
BM Chendi Zhan, Ruxi Qi, Guanghong Wei, Emine Guven-Maiorov, Ruth Nussinov
Protein Engineering Design and Selection, 2016
Identification of Interconnected Markers for T-Cell Acute Lymphoblastic Leukemia
E Guven Maiorov, O Keskin, O Hatirnaz Ng, U Ozbek, A Gursoy
BioMed research international 2013, 2013
Alternative NF-κB pathway activation enhanced by deficient TRAF3 in human papillomavirus (HPV)-associated head and neck cancer
J Zhang, H Cheng, X Yang, EG Maiorov, O Keskin, A Gursoy, R Nussinov, ...
Cancer Research 74 (19 Supplement), 3170-3170, 2014
Novel host-pathogen interactions of Helicobacter pylori and their implications to gastric cancer
EG Maiorov, R Nussinov, CJ Tsai
Cancer Research 77 (13 Supplement), 2678-2678, 2017
RNA-seq, exome-seq, functional RNAi screening and bioinformatics analyses identify molecules promoting aberrant activation of classical and alternative NF-kB pathways in head†…
H Cheng, X Yang, A Saleh, S Cornelius, C Van Waes, Z Chen, ...
Cancer Research 76 (14 Supplement), 81-81, 2016
Altered inflammatory and death pathways in head and neck cell lines model genomic and expression signatures identified in The Cancer Genome Atlas
X Yang, H Cheng, A Saleh, S Cornelius, E Guven-Maiorov, R Nussinov, ...
Cancer Research 75 (15 Supplement), 1111-1111, 2015
Genome-wide RNA and DNA high throughput sequencing reveals proinflammatory and death gene signatures in head and neck squamous cell carcinoma lines with different HPV status
X Yang, H Cheng, H Si, A Saleh, EG Maiorov, J Coupar, O Keskin, ...
Cancer Research 74 (19 Supplement), 3435-3435, 2014
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