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Yu Huang
Yu Huang
Regeneron Pharmaceuticals Inc., Biogen Inc., Boston University School of Medicine
Verified email at regeneron.com
Title
Cited by
Cited by
Year
De Novo Sequencing of Heparan Sulfate Oligosaccharides by Electron-Activated Dissociation
Y Huang, X Yu, Y Mao, CE Costello, J Zaia, C Lin
Analytical chemistry 85 (24), 11979-11986, 2013
582013
Confident assignment of site-specific glycosylation in complex glycoproteins in a single step
K Khatri, GO Staples, N Leymarie, DR Leon, L Turiák, Y Huang, S Yip, ...
Journal of proteome research 13 (10), 4347-4355, 2014
552014
Immunogenic HLA-DR-presented self-peptides identified directly from clinical samples of synovial tissue, synovial fluid, or peripheral blood in patients with rheumatoid …
Q Wang, EE Drouin, C Yao, J Zhang, Y Huang, DR Leon, AC Steere, ...
Journal of proteome research 16 (1), 122-136, 2017
522017
Comparative glycomics of leukocyte glycosaminoglycans
C Shao, X Shi, M White, Y Huang, K Hartshorn, J Zaia
The FEBS journal 280 (10), 2447-2461, 2013
472013
Tandem mass spectrometry of heparan sulfate negative ions: sulfate loss patterns and chemical modification methods for improvement of product ion profiles
X Shi, Y Huang, Y Mao, H Naimy, J Zaia
Journal of the American Society for Mass Spectrometry 23 (9), 1498-1511, 2012
442012
Improved liquid chromatography-MS/MS of heparan sulfate oligosaccharides via chip-based pulsed makeup flow
Y Huang, X Shi, X Yu, N Leymarie, GO Staples, H Yin, K Killeen, J Zaia
Analytical chemistry 83 (21), 8222-8229, 2011
432011
Discovery of a Heparan Sulfate 3-O-Sulfation Specific Peeling Reaction
Y Huang, Y Mao, C Zong, C Lin, GJ Boons, J Zaia
Analytical chemistry 87 (1), 592-600, 2015
392015
A Liquid Chromatography-Mass Spectrometry-based Approach to Characterize the Substrate Specificity of Mammalian Heparanase
Y Mao, Y Huang, JA Buczek-Thomas, CM Ethen, MA Nugent, ZL Wu, ...
Journal of Biological Chemistry 289 (49), 34141-34151, 2014
332014
A Computational Framework for Heparan Sulfate Sequencing Using High-resolution Tandem Mass Spectra
H Hu, Y Huang, Y Mao, X Yu, Y Xu, J Liu, C Zong, GJ Boons, C Lin, Y Xia, ...
Molecular & Cellular Proteomics 13 (9), 2490-2502, 2014
332014
Quantitation and pharmacokinetic modeling of therapeutic antibody quality attributes in human studies
Y Li, M Monine, Y Huang, P Swann, I Nestorov, Y Lyubarskaya
mAbs, 00-00, 2016
282016
Assessing in vivo dynamics of multiple quality attributes from a therapeutic IgG4 monoclonal antibody circulating in cynomolgus monkey
Y Li, Y Huang, J Ferrant, Y Lyubarskaya, Y Zhang, S Li, SL Wu
MAbs 8 (5), 961-968, 2016
242016
Toward unbiased identification and comparative quantification of host cell protein impurities by automated iterative LC–MS/MS (HCP-AIMS) for therapeutic protein development
Y Huang, R Molden, M Hu, H Qiu, N Li
Journal of Pharmaceutical and Biomedical Analysis 200, 114069, 2021
152021
Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single-and multiple-dose monkey pharmacokinetic studies using mass …
X Xu, Y Huang, H Pan, R Molden, H Qiu, TJ Daly, N Li
PloS one 14 (10), e0223899, 2019
152019
High-sensitivity and high-resolution therapeutic antibody charge variant and impurity characterization by microfluidic native capillary electrophoresis-mass spectrometry
Z Wu, H Wang, J Wu, Y Huang, X Zhao, JB Nguyen, MP Rosconi, ...
Journal of Pharmaceutical and Biomedical Analysis 223, 115147, 2023
92023
Bioinformatics of glycosaminoglycans
H Hu, Y Mao, Y Huang, C Lin, J Zaia
Perspectives in Science 11, 40-44, 2017
62017
Oligosaccharide substrate preferences of human extracellular sulfatase Sulf2 using liquid chromatography-mass spectrometry based glycomics approaches
Y Huang, Y Mao, JA Buczek-Thomas, MA Nugent, J Zaia
PloS one 9 (8), e105143, 2014
52014
LC-MS and LC-MS/MS studies of incorporation of 34SO3 into glycosaminoglycan chains by sulfotransferases
X Shi, C Shao, Y Mao, Y Huang, ZL Wu, J Zaia
Glycobiology 23 (8), 969-979, 2013
42013
Host cell protein identification in monoclonal antibody high molecular weight species
M Hu, R Molden, Y Hu, Y Huang, H Qiu, N Li
Journal of Chromatography B 1210, 123448, 2022
32022
Effects of inorganic mercury on the conformation and activity of glutathione S-transferase from Schistosoma japonicum.
XH Huang, Y Huang, HL Gao, JX Yan
Asian Journal of Chemistry 22 (5), 3458-3468, 2010
22010
Size exclusion chromatography for characterizing host cell proteins
H Xiao, N Li, B Zhao, H Tomono, M Hu, R Molden, Y Hu, Y Huang, H Qiu
US Patent App. 18/114,047, 2023
12023
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Articles 1–20