Valerian Kagan
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Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease
BR Stockwell, JPF Angeli, H Bayir, AI Bush, M Conrad, SJ Dixon, S Fulda, ...
Cell 171 (2), 273-285, 2017
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
JP Friedmann Angeli, M Schneider, B Proneth, YY Tyurina, VA Tyurin, ...
Nature cell biology 16 (12), 1180-1191, 2014
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
S Doll, B Proneth, YY Tyurina, E Panzilius, S Kobayashi, I Ingold, M Irmler, ...
Nature chemical biology 13 (1), 91-98, 2017
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
VE Kagan, G Mao, F Qu, JPF Angeli, S Doll, CS Croix, HH Dar, B Liu, ...
Nature chemical biology 13 (1), 81-90, 2017
Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice
AA Shvedova, ER Kisin, R Mercer, AR Murray, VJ Johnson, AI Potapovich, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 289 (5 …, 2005
Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors
VE Kagan, VA Tyurin, J Jiang, YY Tyurina, VB Ritov, AA Amoscato, ...
Nature chemical biology 1 (4), 223-232, 2005
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
CT Chu, J Ji, RK Dagda, JF Jiang, YY Tyurina, AA Kapralov, VA Tyurin, ...
Nature cell biology 15 (10), 1197-1205, 2013
Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol
E Serbinova, V Kagan, D Han, L Packer
Free Radical Biology and Medicine 10 (5), 263-275, 1991
Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation
VE Kagan, NV Konduru, W Feng, BL Allen, J Conroy, Y Volkov, II Vlasova, ...
Nature nanotechnology 5 (5), 354-359, 2010
Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis
AA Shvedova, E Kisin, AR Murray, VJ Johnson, O Gorelik, S Arepalli, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (4 …, 2008
The role of lipid peroxidation in pathogenesis of ischemic damage and the antioxidant protection of the heart. Basic Res Cardiol.
AYV Meerson FZ, Kagan VE, Kozlov YuP, Belkina LM
Basic Res Cardiol. 77 (5), 465-85, 1982
Targeting mitochondria
AT Hoye, JE Davoren, P Wipf, MP Fink, VE Kagan
Accounts of chemical research 41 (1), 87-97, 2008
Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macrophages: role of iron
VE Kagan, YY Tyurina, VA Tyurin, NV Konduru, AI Potapovich, AN Osipov, ...
Toxicology letters 165 (1), 88-100, 2006
Lipid accumulation and dendritic cell dysfunction in cancer
DL Herber, W Cao, Y Nefedova, SV Novitskiy, S Nagaraj, VA Tyurin, ...
Nature medicine 16 (8), 880-886, 2010
PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals
SE Wenzel, YY Tyurina, J Zhao, CMS Croix, HH Dar, G Mao, VA Tyurin, ...
Cell 171 (3), 628-641. e26, 2017
The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis
M Hüttemann, P Pecina, M Rainbolt, TH Sanderson, VE Kagan, ...
Mitochondrion 11 (3), 369-381, 2011
Dihydrolipoic acid—a universal antioxidant both in the membrane and in the aqueous phase: reduction of peroxyl, ascorbyl and chromanoxyl radicals
VE Kagan, A Shvedova, E Serbinova, S Khan, C Swanson, R Powell, ...
Biochemical pharmacology 44 (8), 1637-1649, 1992
Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress
AA Shvedova, A Pietroiusti, B Fadeel, VE Kagan
Toxicology and applied pharmacology 261 (2), 121-133, 2012
Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling.
PL Kagan V, Serbinova E
Biochem Biophys Res Commun. 169 (3), 851-7, 1990
FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation
MM Gaschler, AA Andia, H Liu, JM Csuka, B Hurlocker, CA Vaiana, ...
Nature chemical biology 14 (5), 507-515, 2018
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