Direct comparison of flow-FISH and qPCR as diagnostic tests for telomere length measurement in humans F Gutierrez-Rodrigues, BA Santana-Lemos, PS Scheucher, ... PloS one 9 (11), e113747, 2014 | 166 | 2014 |
(+) α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo GAS Dos Santos, RS Abreu e Lima, CR Pestana, ASG Lima, ... Leukemia 26 (3), 451-460, 2012 | 68 | 2012 |
Increased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia HL Gimenes-Teixeira, AR Lucena-Araujo, GA Dos Santos, DL Zanette, ... Experimental hematology & oncology 2, 1-8, 2013 | 64 | 2013 |
Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity CH Thome, GA Dos Santos, GA Ferreira, PS Scheucher, C Izumi, ... Molecular & Cellular Proteomics 11 (12), 1898-1912, 2012 | 59 | 2012 |
TGF-beta/atRA-induced Tregs express a selected set of microRNAs involved in the repression of transcripts related to Th17 differentiation JLS Schiavinato, R Haddad, F Saldanha-Araujo, J Baiochi, AG Araujo, ... Scientific reports 7 (1), 3627, 2017 | 40 | 2017 |
NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2V617F-positive myeloproliferative neoplasm cells BA Fenerich, JC Fernandes, APN Rodrigues Alves, JL Coelho-Silva, ... Signal transduction and targeted therapy 5 (1), 5, 2020 | 30 | 2020 |
IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells APNR Alves, JC Fernandes, BA Fenerich, JL Coelho-Silva, PS Scheucher, ... Cancer Letters 456, 59-68, 2019 | 30 | 2019 |
Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms JA Machado-Neto, BA Fenerich, R Scopim-Ribeiro, CA Eide, ... Cell death & disease 9 (3), 311, 2018 | 23 | 2018 |
Reversine triggers mitotic catastrophe and apoptosis in K562 cells APNR Alves, JA Machado-Neto, PS Scheucher, HH Paiva, BP Simões, ... Leukemia Research 48, 26-31, 2016 | 19 | 2016 |
Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2V617F cells JA Machado-Neto, JL Coelho-Silva, FPS Santos, PS Scheucher, ... Investigational New Drugs 38, 733-745, 2020 | 17 | 2020 |
DE THÉ H, PANDOLFI PP, CURTI C, REGO EM:(+) alpha-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA … GA Dos Santos, ELRS ABREU, CR Pestana, AS Lima, PS Scheucher, ... Leukemia 26, 451-460, 2012 | 17 | 2012 |
Apoptosis induction by (+) α-tocopheryl succinate in the absence or presence of all-trans retinoic acid and arsenic trioxide in NB4, NB4-R2 and primary APL cells RA Freitas, GAS dos Santos, HLG Teixeira, PS Scheucher, ... Leukemia research 33 (7), 958-963, 2009 | 16 | 2009 |
Interaction of 10-(octyloxy) decyl-2-(trimethylammonium) ethyl phosphate with mimetic membranes and cytotoxic effect on leukemic cells GA dos Santos, CH Thomé, GA Ferreira, JS Yoneda, TM Nobre, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (9), 1714-1723, 2010 | 15 | 2010 |
Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells JA Machado-Neto, APNR Alves, JC Fernandes, JL Coelho-Silva, ... Heliyon 3 (9), 2017 | 14 | 2017 |
NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia R Scopim-Ribeiro, JA Machado-Neto, CA Eide, JL Coelho-Silva, ... Investigational New Drugs 39, 736-746, 2021 | 10 | 2021 |
The combination of gefitinib with ATRA and ATO induces myeloid differentiation in acute promyelocytic leukemia resistant cells LY Almeida, DA Pereira-Martins, I Weinhäuser, C Ortiz, LA Cândido, ... Frontiers in oncology 11, 686445, 2021 | 9 | 2021 |
Characterization of leukemic stem cells in AML cell lines using ALDH staining MTL Benício, PS Scheucher, AB Garcia, RP Falcao, EM Rego Blood 122 (21), 5409, 2013 | 9 | 2013 |
STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells HP Vicari, JL Coelho-Silva, DA Pereira-Martins, AR Lucena-Araujo, ... Investigational New Drugs, 1-15, 2022 | 8 | 2022 |
Asynchronous expression of myeloid antigens in leukemic cells in a PML/RARalpha transgenic mouse model BAA Santana, MC Pintão, RS Lima, PS Scheucher, GAS Santos, ... Brazilian journal of medical and biological research 39, 615-620, 2006 | 7 | 2006 |
Eltrombopag preferentially expands haematopoietic multipotent progenitors in human aplastic anaemia B Quintino de Oliveira, LFB Catto, BAA Santana, MF Tellechea, ... British Journal of Haematology 193 (2), 410-414, 2021 | 6 | 2021 |