Jialing Lin
Jialing Lin
University of Oklahoma Health Sciences Center
Verified email at - Homepage
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Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes
B Leber, J Lin, DW Andrews
Apoptosis 12, 897-911, 2007
Bcl‐2 changes conformation to inhibit Bax oligomerization
PJ Dlugosz, LP Billen, MG Annis, W Zhu, Z Zhang, J Lin, B Leber, ...
The EMBO journal 25 (11), 2287-2296, 2006
The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process
H Do, D Falcone, J Lin, DW Andrews, AE Johnson
Cell 85 (3), 369-378, 1996
Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration
S Liao, J Lin, H Do, AE Johnson
Cell 90 (1), 31-41, 1997
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
SK Kolluri, X Zhu, X Zhou, B Lin, Y Chen, K Sun, X Tian, J Town, X Cao, ...
Cancer cell 14 (4), 285-298, 2008
Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2
C Tan, PJ Dlugosz, J Peng, Z Zhang, SM Lapolla, SM Plafker, ...
Journal of Biological Chemistry 281 (21), 14764-14775, 2006
Still embedded together binding to membranes regulates Bcl-2 protein interactions
B Leber, J Lin, DW Andrews
Oncogene 29 (38), 5221-5230, 2010
Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens
JJ Flanagan, JC Chen, Y Miao, Y Shao, J Lin, PE Bock, AE Johnson
Journal of biological chemistry 278 (20), 18628-18637, 2003
Cotranslational protein integration into the ER membrane is mediated by the binding of nascent chains to translocon proteins
PJ McCormick, Y Miao, Y Shao, J Lin, AE Johnson
Molecular cell 12 (2), 329-341, 2003
Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax
Z Zhang, SM Lapolla, MG Annis, M Truscott, GJ Roberts, Y Miao, Y Shao, ...
Journal of Biological Chemistry 279 (42), 43920-43928, 2004
BH 3‐in‐groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes
Z Zhang, S Subramaniam, J Kale, C Liao, B Huang, H Brahmbhatt, ...
The EMBO journal 35 (2), 208-236, 2016
Bax forms an oligomer via separate, yet interdependent, surfaces
Z Zhang, W Zhu, SM Lapolla, Y Miao, Y Shao, M Falcone, D Boreham, ...
Journal of Biological Chemistry 285 (23), 17614-17627, 2010
Bcl-2 and Bax interact via the BH1–3 groove-BH3 motif interface and a novel interface involving the BH4 motif
J Ding, Z Zhang, GJ Roberts, M Falcone, Y Miao, Y Shao, XC Zhang, ...
Journal of Biological Chemistry 285 (37), 28749-28763, 2010
Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate
K Ma, Z Zhang, R Chang, H Cheng, C Mu, T Zhao, L Chen, C Zhang, ...
Cell Death & Differentiation 27 (3), 1036-1051, 2020
A small-molecule inhibitor of Bax and Bak oligomerization prevents genotoxic cell death and promotes neuroprotection
X Niu, H Brahmbhatt, P Mergenthaler, Z Zhang, J Sang, M Daude, ...
Cell chemical biology 24 (4), 493-506. e5, 2017
sHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell
D Tian, SG Das, JM Doshi, J Peng, J Lin, C Xing
Cancer letters 259 (2), 198-208, 2008
After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial …
J Ding, BHM Mooers, Z Zhang, J Kale, D Falcone, J McNichol, B Huang, ...
Journal of Biological Chemistry 289 (17), 11873-11896, 2014
Stable SNARE complex prior to evoked synaptic vesicle fusion revealed by fluorescence resonance energy transfer
Z Xia, Q Zhou, J Lin, Y Liu
Journal of Biological Chemistry 276 (3), 1766-1771, 2001
tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation
J Peng, C Tan, GJ Roberts, O Nikolaeva, Z Zhang, SM Lapolla, ...
Journal of Biological Chemistry 281 (47), 35802-35811, 2006
A Novel Integration Signal That Is Composed of Two Transmembrane Segments Is Required to Integrate the Neurospora Plasma Membrane H+-ATPase into Microsomes (∗)
J Lin, R Addison
Journal of Biological Chemistry 270 (12), 6935-6941, 1995
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