The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum NN Alder, Y Shen, JL Brodsky, LM Hendershot, AE Johnson The Journal of cell biology 168 (3), 389-399, 2005 | 226 | 2005 |
A detergent-free strategy for the reconstitution of active enzyme complexes from native biological membranes into nanoscale discs AR Long, CC O’Brien, K Malhotra, CT Schwall, AD Albert, A Watts, ... BMC biotechnology 13, 1-10, 2013 | 174 | 2013 |
Cotranslational membrane protein biogenesis at the endoplasmic reticulum NN Alder, AE Johnson Journal of Biological Chemistry 279 (22), 22787-22790, 2004 | 165 | 2004 |
The stability and activity of respiratory Complex II is cardiolipin-dependent CT Schwall, VL Greenwood, NN Alder Biochimica et Biophysica Acta (BBA)-Bioenergetics 1817 (9), 1588-1596, 2012 | 151 | 2012 |
Energetics of protein transport across biological membranes: a study of the thylakoid ΔpH-dependent/cpTat pathway NN Alder, SM Theg Cell 112 (2), 231-242, 2003 | 148 | 2003 |
Unremodeled and remodeled cardiolipin are functionally indistinguishable in yeast MG Baile, M Sathappa, YW Lu, E Pryce, K Whited, JM McCaffery, X Han, ... Journal of Biological Chemistry 289 (3), 1768-1778, 2014 | 142 | 2014 |
Fluorescence mapping of mitochondrial TIM23 complex reveals a water-facing, substrate-interacting helix surface NN Alder, RE Jensen, AE Johnson Cell 134 (3), 439-450, 2008 | 127 | 2008 |
The ionization properties of cardiolipin and its variants in model bilayers M Sathappa, NN Alder Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (6), 1362-1372, 2016 | 106 | 2016 |
Targeting mitochondria with methylene blue protects mice against acetaminophen‐induced liver injury KK Lee, N Imaizumi, SR Chamberland, NN Alder, UA Boelsterli Hepatology 61 (1), 326-336, 2015 | 105 | 2015 |
Mitochondrial Ca2+ influx targets cardiolipin to disintegrate respiratory chain complex II for cell death induction MS Hwang, CT Schwall, E Pazarentzos, C Datler, NN Alder, S Grimm Cell Death & Differentiation 21 (11), 1733-1745, 2014 | 105 | 2014 |
The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action W Mitchell, EA Ng, JD Tamucci, KJ Boyd, M Sathappa, A Coscia, M Pan, ... Journal of Biological Chemistry 295 (21), 7452-7469, 2020 | 98 | 2020 |
Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc1 complex function E Calzada, E Avery, PN Sam, A Modak, C Wang, JM McCaffery, X Han, ... Nature communications 10 (1), 1432, 2019 | 95 | 2019 |
Mechanism of amylin fibrillization enhancement by heparin S Jha, SM Patil, J Gibson, CE Nelson, NN Alder, AT Alexandrescu Journal of Biological Chemistry 286 (26), 22894-22904, 2011 | 90 | 2011 |
Buckling under pressure: curvature-based lipid segregation and stability modulation in cardiolipin-containing bilayers KJ Boyd, NN Alder, ER May Langmuir 33 (27), 6937-6946, 2017 | 85 | 2017 |
Reduction of elevated proton leak rejuvenates mitochondria in the aged cardiomyocyte H Zhang, NN Alder, W Wang, H Szeto, DJ Marcinek, PS Rabinovitch Elife 9, e60827, 2020 | 84 | 2020 |
Structural changes in the mitochondrial Tim23 channel are coupled to the proton-motive force K Malhotra, M Sathappa, JS Landin, AE Johnson, NN Alder Nature Structural & Molecular Biology 20 (8), 965-972, 2013 | 82 | 2013 |
The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import AJ Davis, NN Alder, RE Jensen, AE Johnson Molecular biology of the cell 18 (2), 475-486, 2007 | 78 | 2007 |
Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatocytes KK Lee, K Fujimoto, C Zhang, CT Schwall, NN Alder, CA Pinkert, ... Free Radical Biology and Medicine 65, 584-594, 2013 | 75 | 2013 |
Green proteorhodopsin reconstituted into nanoscale phospholipid bilayers (nanodiscs) as photoactive monomers MJ Ranaghan, CT Schwall, NN Alder, RR Birge Journal of the American Chemical Society 133 (45), 18318-18327, 2011 | 74 | 2011 |
Quaternary structure of the mitochondrial TIM23 complex reveals dynamic association between Tim23p and other subunits NN Alder, J Sutherland, AI Buhring, RE Jensen, AE Johnson Molecular biology of the cell 19 (1), 159-170, 2008 | 74 | 2008 |