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David K Breslow
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Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise
JRS Newman, S Ghaemmaghami, J Ihmels, DK Breslow, M Noble, ...
Nature 441 (7095), 840-846, 2006
17352006
Orm family proteins mediate sphingolipid homeostasis
DK Breslow, SR Collins, B Bodenmiller, R Aebersold, K Simons, ...
Nature 463 (7284), 1048-1053, 2010
6722010
A comprehensive strategy enabling high-resolution functional analysis of the yeast genome
DK Breslow, DM Cameron, SR Collins, M Schuldiner, J Stewart-Ornstein, ...
Nature methods 5 (8), 711-718, 2008
6192008
Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae
FM Roelants, DK Breslow, A Muir, JS Weissman, J Thorner
Proceedings of the National Academy of Sciences 108 (48), 19222-19227, 2011
3102011
Membranes in balance: mechanisms of sphingolipid homeostasis
DK Breslow, JS Weissman
Molecular cell 40 (2), 267-279, 2010
2942010
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
S Seo, Q Zhang, K Bugge, DK Breslow, CC Searby, MV Nachury, ...
PLoS genetics 7 (11), e1002358, 2011
2292011
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3
GM Liew, F Ye, AR Nager, JP Murphy, JS Lee, M Aguiar, DK Breslow, ...
Developmental cell 31 (3), 265-278, 2014
2082014
An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier
DK Breslow, EF Koslover, F Seydel, AJ Spakowitz, MV Nachury
Journal of Cell Biology 203 (1), 129-147, 2013
1992013
Mechanism and regulation of centriole and cilium biogenesis
DK Breslow, AJ Holland
Annual review of biochemistry 88, 691-724, 2019
1872019
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
DK Breslow, S Hoogendoorn, AR Kopp, DW Morgens, BK Vu, ...
Nature genetics 50 (3), 460-471, 2018
1562018
Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors
F Ye, DK Breslow, EF Koslover, AJ Spakowitz, WJ Nelson, MV Nachury
Elife 2, e00654, 2013
1392013
Sphingolipid homeostasis in the endoplasmic reticulum and beyond
DK Breslow
Cold Spring Harbor perspectives in biology 5 (4), a013326, 2013
862013
Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
AK Ganga, MC Kennedy, ME Oguchi, S Gray, KE Oliver, TA Knight, ...
Current Biology 31 (13), 2895-2905. e7, 2021
322021
Primary cilia: how to keep the riff-raff in the plasma membrane
DK Breslow, MV Nachury
Current biology 21 (11), R434-R436, 2011
192011
Analysis of soluble protein entry into primary cilia using semipermeabilized cells
DK Breslow, MV Nachury
Methods in cell biology 127, 203-221, 2015
142015
Pathogenic RAB34 variants impair primary cilium assembly and cause a novel oral-facial-digital syndrome
AL Bruel, AK Ganga, L Nosková, I Valenzuela, J Martinovic, Y Duffourd, ...
Human Molecular Genetics 32 (18), 2822-2831, 2023
42023
Rab34 GTPase mediates ciliary membrane biogenesis in the intracellular ciliogenesis pathway
AK Ganga, MC Kennedy, ME Oguchi, SD Gray, KE Oliver, TA Knight, ...
bioRxiv, 2020.10. 29.360891, 2020
32020
A comprehensive portrait of cilia and ciliopathies from a CRISPR-based screen for hedgehog signaling
DK Breslow, S Hoogendoorn, AR Kopp, DW Morgens, BK Vu, K Han, A Li, ...
bioRxiv, 156059, 2017
22017
A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
AK Ganga, LK Sweeney, A Rubio-Ramos, CS Bishop, V Hamel, ...
bioRxiv, 2024.04. 02.587836, 2024
2024
Pericentrin Knocks Down Cilia in Trisomy 21
DK Breslow
Developmental Cell 46 (5), 527-528, 2018
2018
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