| Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017 | 650 | 2017 |
| RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis E Gonzalez-Suarez, AP Jacob, J Jones, R Miller, MP Roudier-Meyer, ... Nature 468 (7320), 103-107, 2010 | 618 | 2010 |
| Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes E González‐Suárez, E Samper, A Ramírez, JM Flores, J Martín‐Caballero, ... The EMBO journal, 2001 | 445 | 2001 |
| Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis E González-Suárez, E Samper, JM Flores, MA Blasco Nature genetics 26 (1), 114-117, 2000 | 432 | 2000 |
| Patient-derived xenograft (PDX) models in basic and translational breast cancer research LE Dobrolecki, SD Airhart, DG Alferez, S Aparicio, F Behbod, ... Cancer and Metastasis Reviews 35, 547-573, 2016 | 252 | 2016 |
| RANK induces epithelial–mesenchymal transition and stemness in human mammary epithelial cells and promotes tumorigenesis and metastasis M Palafox, I Ferrer, P Pellegrini, S Vila, S Hernandez-Ortega, ... Cancer research 72 (11), 2879-2888, 2012 | 220 | 2012 |
| BRCA1 CpG island hypermethylation predicts sensitivity to poly (adenosine diphosphate)-ribose polymerase inhibitorsBRCA1 CpG island hypermethylation predicts sensitivity to … J Veeck, S Ropero, F Setien, E Gonzalez-Suarez, A Osorio, J Benitez, ... Journal of Clinical Oncology, 2010, vol. 28, num. 29, p. e563-e564, 2010 | 185 | 2010 |
| BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation HA Arnett, SS Escobar, E Gonzalez-Suarez, AL Budelsky, LA Steffen, ... The Journal of Immunology 178 (3), 1523-1533, 2007 | 173 | 2007 |
| RANKL/RANK control Brca1 mutation-driven mammary tumors V Sigl, K Owusu-Boaitey, PA Joshi, A Kavirayani, G Wirnsberger, ... Cell research 26 (7), 761-774, 2016 | 158 | 2016 |
| RANK overexpression in transgenic mice with mouse mammary tumor virus promoter-controlled RANK increases proliferation and impairs alveolar differentiation in the mammary … E Gonzalez-Suarez, D Branstetter, A Armstrong, H Dinh, H Blumberg, ... Molecular and cellular biology 27 (4), 1442-1454, 2007 | 150 | 2007 |
| Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice E Gonzalez-Suarez, C Geserick, JM Flores, MA Blasco Oncogene 24 (13), 2256-2270, 2005 | 133 | 2005 |
| Normal telomere length and chromosomal end capping in poly (ADP-ribose) polymerase–deficient mice and primary cells despite increased chromosomal instability E Samper, FA Goytisolo, JM Murcia, E González-Suárez, JC Cigudosa, ... The Journal of Cell Biology 154 (1), 49-60, 2001 | 120 | 2001 |
| Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development E González-Suárez, JM Flores, MA Blasco Molecular and cellular biology 22 (20), 7291-7301, 2002 | 115 | 2002 |
| Management of bone health in solid tumours: From bisphosphonates to a monoclonal antibody R von Moos, L Costa, E Gonzalez-Suarez, E Terpos, D Niepel, JJ Body Cancer treatment reviews 76, 57-67, 2019 | 100 | 2019 |
| Linkage of DNA methylation quantitative trait loci to human cancer risk H Heyn, S Sayols, C Moutinho, E Vidal, JV Sanchez-Mut, OA Stefansson, ... Cell reports 7 (2), 331-338, 2014 | 100 | 2014 |
| Targeting p38α increases DNA damage, chromosome instability, and the anti-tumoral response to taxanes in breast cancer cells B Cánovas, A Igea, AA Sartori, RR Gomis, TT Paull, M Isoda, ... Cancer cell 33 (6), 1094-1110. e8, 2018 | 90 | 2018 |
| Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-β signaling C Geserick, A Tejera, E Gonzalez-Suarez, P Klatt, MA Blasco Oncogene 25 (31), 4310-4319, 2006 | 90 | 2006 |
| Targeting RANKL in metastasis WC Dougall, I Holen, EG Suarez BoneKEy reports 3, 2014 | 88 | 2014 |
| A comprehensive DNA methylation profile of epithelial-to-mesenchymal transition FJ Carmona, V Davalos, E Vidal, A Gomez, H Heyn, Y Hashimoto, ... Cancer research 74 (19), 5608-5619, 2014 | 79 | 2014 |
| Resistance to taxanes in triple-negative breast cancer associates with the dynamics of a CD49f+ tumor-initiating population J Gómez-Miragaya, M Palafox, L Paré, G Yoldi, I Ferrer, S Vila, P Galván, ... Stem cell reports 8 (5), 1392-1407, 2017 | 78 | 2017 |
