Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice SA Villeda, KE Plambeck, J Middeldorp, JM Castellano, KI Mosher, J Luo, ... Nature medicine 20 (6), 659-663, 2014 | 1170 | 2014 |
Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease DA Simmons, M Casale, B Alcon, NHA Pham, N Narayan, G Lynch Glia 55 (10), 1074-1084, 2007 | 314 | 2007 |
Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice DA Simmons, CS Rex, L Palmer, V Pandyarajan, V Fedulov, CM Gall, ... Proceedings of the National Academy of Sciences 106 (12), 4906-4911, 2009 | 298 | 2009 |
Forebrain expression of c-fos due to active maternal behaviour in lactating rats JS Lonstein, DA Simmons, JM Swann, JM Stern Neuroscience 82 (1), 267-281, 1997 | 249 | 1997 |
Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation DA Simmons, FM Lartey, E Schüler, M Rafat, G King, A Kim, R Ko, ... Radiotherapy and Oncology 139, 4-10, 2019 | 248 | 2019 |
Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease G Lynch, EA Kramar, CS Rex, Y Jia, D Chappas, CM Gall, DA Simmons Journal of Neuroscience 27 (16), 4424-4434, 2007 | 216 | 2007 |
Postnatal development of inflammation in a murine model of Niemann–Pick type C disease: immunohistochemical observations of microglia and astroglia M Baudry, Y Yao, D Simmons, J Liu, X Bi Experimental neurology 184 (2), 887-903, 2003 | 205 | 2003 |
Functions of the caudal periaqueductal gray in lactating rats: kyphosis, lordosis, maternal aggression, and fearfulness. JS Lonstein, DA Simmons, JM Stern Behavioral neuroscience 112 (6), 1502, 1998 | 192 | 1998 |
Evidence that long-term potentiation occurs within individual hippocampal synapses during learning V Fedulov, CS Rex, DA Simmons, L Palmer, CM Gall, G Lynch Journal of Neuroscience 27 (30), 8031-8039, 2007 | 185 | 2007 |
A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease DA Simmons, NP Belichenko, T Yang, C Condon, M Monbureau, ... Journal of Neuroscience 33 (48), 18712-18727, 2013 | 156 | 2013 |
A small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model JK Knowles, DA Simmons, TVV Nguyen, L Vander Griend, Y Xie, H Zhang, ... Neurobiology of aging 34 (8), 2052-2063, 2013 | 131 | 2013 |
CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice BL Apostol, DA Simmons, C Zuccato, K Illes, J Pallos, M Casale, ... Molecular and Cellular Neuroscience 39 (1), 8-20, 2008 | 94 | 2008 |
A Small Molecule p75NTR Ligand, LM11A-31, Reverses Cholinergic Neurite Dystrophy in Alzheimer's Disease Mouse Models with Mid- to Late-Stage Disease … DA Simmons, JK Knowles, NP Belichenko, G Banerjee, C Finkle, ... PloS one 9 (8), e102136, 2014 | 93 | 2014 |
BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats EA Kramár, LY Chen, JC Lauterborn, DA Simmons, CM Gall, G Lynch Neurobiology of aging 33 (4), 708-719, 2012 | 88 | 2012 |
Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice DA Simmons, RA Mehta, JC Lauterborn, CM Gall, G Lynch Neurobiology of disease 41 (2), 436-444, 2011 | 79 | 2011 |
A small molecule p75NTR ligand normalizes signalling and reduces Huntington’s disease phenotypes in R6/2 and BACHD mice DA Simmons, NP Belichenko, EC Ford, S Semaan, M Monbureau, ... Human molecular genetics 25 (22), 4920-4938, 2016 | 63 | 2016 |
Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: restoration by the neuroprotective compound CEP-1347 P Conforti, C Ramos, BL Apostol, DA Simmons, HP Nguyen, O Riess, ... Molecular and Cellular Neuroscience 39 (1), 1-7, 2008 | 58 | 2008 |
GABA and glutamate in mating‐activated cells in the preoptic area and medial amygdala of male gerbils DA Simmons, P Yahr Journal of Comparative Neurology 459 (3), 290-300, 2003 | 46 | 2003 |
Modulating neurotrophin receptor signaling as a therapeutic strategy for Huntington’s disease DA Simmons Journal of Huntington's disease 6 (4), 303-325, 2017 | 42 | 2017 |
DP‐155, a lecithin derivative of indomethacin, is a novel nonsteroidal antiinflammatory drug for analgesia and Alzheimer's disease therapy E Dvir, A Elman, D Simmons, I Shapiro, R Duvdevani, A Dahan, ... CNS drug reviews 13 (2), 260-277, 2007 | 42 | 2007 |