Kuan-Ting, Lin
Kuan-Ting, Lin
Skyhawk Therapeutics
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Targeting an RNA-binding protein network in acute myeloid leukemia
E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee, K Hockemeyer, ...
Cancer cell 35 (3), 369-384. e7, 2019
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis
A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ...
Nature 574 (7777), 273-277, 2019
Differential functions of splicing factors in mammary transformation and breast cancer metastasis
SH Park, M Brugiolo, M Akerman, S Das, L Urbanski, A Geier, ...
Cell reports 29 (9), 2672-2688. e7, 2019
Gene expression-based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma
MH Chen, WLR Yang, KT Lin, CH Liu, YW Liu, KW Huang, PMH Chang, ...
PloS one 6 (11), e27186, 2011
BIOADI: a machine learning approach to identifying abbreviations and definitions in biological literature
CJ Kuo, MHT Ling, KT Lin, CN Hsu
BMC bioinformatics 10, 1-10, 2009
Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (E ncyclopedia of H epatocellular C arcinoma genes O nline)
CN Hsu, JM Lai, CH Liu, HH Tseng, CY Lin, KT Lin, HH Yeh, TY Sung, ...
BMC bioinformatics 8, 1-12, 2007
Recurrent SRSF2 mutations in MDS affect both splicing and NMD
MA Rahman, KT Lin, RK Bradley, O Abdel-Wahab, AR Krainer
Genes & Development 34 (5-6), 413-427, 2020
Hybridization-mediated off-target effects of splice-switching antisense oligonucleotides
J Scharner, WK Ma, Q Zhang, KT Lin, F Rigo, CF Bennett, AR Krainer
Nucleic acids research 48 (2), 802-816, 2020
Rich feature set, unification of bidirectional parsing and dictionary filtering for high F-score gene mention tagging
CJ Kuo, YM Chang, HS Huang, KT Lin, BH Yang, YS Lin, CN Hsu, ...
Proceedings of the second BioCreative challenge evaluation workshop 23, 105-107, 2007
Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep whole-transcriptome sequencing
KT Lin, YJ Shann, GY Chau, CN Hsu, CY Huang
Oncogene 33 (39), 4786-4794, 2014
PSI-Sigma: a comprehensive splicing-detection method for short-read and long-read RNA-seq analysis
KT Lin, AR Krainer
Bioinformatics 35 (23), 5048-5054, 2019
ASO-based PKM splice-switching therapy inhibits hepatocellular carcinoma growth
WK Ma, DM Voss, J Scharner, ASH Costa, KT Lin, HY Jeon, JE Wilkinson, ...
Cancer research 82 (5), 900-915, 2022
Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma
CH Liu, TC Chen, GY Chau, YH Jan, CH Chen, CN Hsu, KT Lin, YL Juang, ...
Molecular & Cellular Proteomics 12 (5), 1335-1349, 2013
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
HCY Chen TC, Lin KT, Chen CH, Lee SA, Lee PY, Liu YW, Kuo YL, Wang FS, Lai JM
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer
A Jbara, KT Lin, C Stossel, Z Siegfried, H Shqerat, A Amar-Schwartz, ...
Nature 617 (7959), 147-153, 2023
In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non–small‐cell lung cancer
TH Huang, ATH Wu, TS Cheng, KT Lin, CJ Lai, HW Hsieh, PMH Chang, ...
Journal of Cellular and Molecular Medicine 23 (12), 8184-8195, 2019
A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma
KT Lin, WK Ma, J Scharner, YR Liu, AR Krainer
Genome research 28 (3), 275-284, 2018
Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway
HJ Jhuang, WH Hsu, KT Lin, SL Hsu, FS Wang, CK Chou, KH Lee, ...
Oncotarget 6 (10), 7788, 2015
From NPC therapeutic target identification to potential treatment strategy
MY Lan, CL Chen, KT Lin, SA Lee, WLR Yang, CN Hsu, JC Wu, CY Ho, ...
Molecular cancer therapeutics 9 (9), 2511-2523, 2010
Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer
L Wan, KT Lin, MA Rahman, Y Ishigami, Z Wang, MA Jensen, ...
Cancer discovery 13 (7), 1678-1695, 2023
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