Targeting an RNA-binding protein network in acute myeloid leukemia E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee, K Hockemeyer, ... Cancer cell 35 (3), 369-384. e7, 2019 | 285 | 2019 |
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ... Nature 574 (7777), 273-277, 2019 | 206 | 2019 |
Differential functions of splicing factors in mammary transformation and breast cancer metastasis SH Park, M Brugiolo, M Akerman, S Das, L Urbanski, A Geier, ... Cell reports 29 (9), 2672-2688. e7, 2019 | 99 | 2019 |
Gene expression-based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma MH Chen, WLR Yang, KT Lin, CH Liu, YW Liu, KW Huang, PMH Chang, ... PloS one 6 (11), e27186, 2011 | 86 | 2011 |
BIOADI: a machine learning approach to identifying abbreviations and definitions in biological literature CJ Kuo, MHT Ling, KT Lin, CN Hsu BMC bioinformatics 10, 1-10, 2009 | 80 | 2009 |
Recurrent SRSF2 mutations in MDS affect both splicing and NMD MA Rahman, KT Lin, RK Bradley, O Abdel-Wahab, AR Krainer Genes & Development 34 (5-6), 413-427, 2020 | 72 | 2020 |
Hybridization-mediated off-target effects of splice-switching antisense oligonucleotides J Scharner, WK Ma, Q Zhang, KT Lin, F Rigo, CF Bennett, AR Krainer Nucleic acids research 48 (2), 802-816, 2020 | 72 | 2020 |
Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (E ncyclopedia of H epatocellular C arcinoma genes O nline) CN Hsu, JM Lai, CH Liu, HH Tseng, CY Lin, KT Lin, HH Yeh, TY Sung, ... BMC bioinformatics 8, 1-12, 2007 | 60 | 2007 |
ASO-based PKM splice-switching therapy inhibits hepatocellular carcinoma growth WK Ma, DM Voss, J Scharner, ASH Costa, KT Lin, HY Jeon, JE Wilkinson, ... Cancer research 82 (5), 900-915, 2022 | 58 | 2022 |
Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep whole-transcriptome sequencing KT Lin, YJ Shann, GY Chau, CN Hsu, CY Huang Oncogene 33 (39), 4786-4794, 2014 | 53 | 2014 |
Rich feature set, unification of bidirectional parsing and dictionary filtering for high F-score gene mention tagging CJ Kuo, YM Chang, HS Huang, KT Lin, BH Yang, YS Lin, CN Hsu, ... Proceedings of the second BioCreative challenge evaluation workshop 23, 105-107, 2007 | 53 | 2007 |
PSI-Sigma: a comprehensive splicing-detection method for short-read and long-read RNA-seq analysis KT Lin, AR Krainer Bioinformatics 35 (23), 5048-5054, 2019 | 49 | 2019 |
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer A Jbara, KT Lin, C Stossel, Z Siegfried, H Shqerat, A Amar-Schwartz, ... Nature 617 (7959), 147-153, 2023 | 46 | 2023 |
Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma CH Liu, TC Chen, GY Chau, YH Jan, CH Chen, CN Hsu, KT Lin, YL Juang, ... Molecular & Cellular Proteomics 12 (5), 1335-1349, 2013 | 36 | 2013 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network HCY Chen TC, Lin KT, Chen CH, Lee SA, Lee PY, Liu YW, Kuo YL, Wang FS, Lai JM JOURNAL OF PROTEOME RESEARCH, 2014 | 34 | 2014 |
Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer L Wan, KT Lin, MA Rahman, Y Ishigami, Z Wang, MA Jensen, ... Cancer discovery 13 (7), 1678-1695, 2023 | 29 | 2023 |
In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non–small‐cell lung cancer TH Huang, ATH Wu, TS Cheng, KT Lin, CJ Lai, HW Hsieh, PMH Chang, ... Journal of Cellular and Molecular Medicine 23 (12), 8184-8195, 2019 | 28 | 2019 |
A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma KT Lin, WK Ma, J Scharner, YR Liu, AR Krainer Genome research 28 (3), 275-284, 2018 | 23 | 2018 |
SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer HL Ma, M Bizet, CS Da Costa, F Murisier, EJ de Bony, MK Wang, ... Molecular cell 83 (23), 4239-4254. e10, 2023 | 19 | 2023 |
Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway HJ Jhuang, WH Hsu, KT Lin, SL Hsu, FS Wang, CK Chou, KH Lee, ... Oncotarget 6 (10), 7788, 2015 | 19 | 2015 |