Syk-and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17 S LeibundGut-Landmann, O Groß, MJ Robinson, F Osorio, EC Slack, ... Nature immunology 8 (6), 630-638, 2007 | 1434 | 2007 |
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence O Gross, H Poeck, M Bscheider, C Dostert, N Hannesschläger, S Endres, ... Nature 459 (7245), 433-436, 2009 | 1101 | 2009 |
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity O Gross, A Gewies, K Finger, M Schäfer, T Sparwasser, C Peschel, ... Nature 442 (7103), 651-656, 2006 | 1022 | 2006 |
The inflammasome: an integrated view O Gross, CJ Thomas, G Guarda, J Tschopp Immunological reviews 243 (1), 136-151, 2011 | 909 | 2011 |
A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections EO Glocker, A Hennigs, M Nabavi, AA Schäffer, C Woellner, U Salzer, ... New England Journal of Medicine 361 (18), 1727-1735, 2009 | 899 | 2009 |
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation MJC Jordão, R Sankowski, SM Brendecke, Sagar, G Locatelli, YH Tai, ... Science 363 (6425), eaat7554, 2019 | 718 | 2019 |
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ... Nature immunology 11 (1), 63-69, 2010 | 668 | 2010 |
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection MJ Robinson, F Osorio, M Rosas, RP Freitas, E Schweighoffer, O Groß, ... Journal of Experimental Medicine 206 (9), 2037-2051, 2009 | 575 | 2009 |
Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1 O Groß, AS Yazdi, CJ Thomas, M Masin, LX Heinz, G Guarda, M Quadroni, ... Immunity 36 (3), 388-400, 2012 | 569 | 2012 |
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation JE Vince, WWL Wong, I Gentle, KE Lawlor, R Allam, L O'Reilly, K Mason, ... Immunity 36 (2), 215-227, 2012 | 539 | 2012 |
Malarial hemozoin is a Nalp3 inflammasome activating danger signal C Dostert, G Guarda, JF Romero, P Menu, O Gross, A Tardivel, ML Suva, ... PloS one 4 (8), e6510, 2009 | 480 | 2009 |
K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria CJ Groß, R Mishra, KS Schneider, G Médard, J Wettmarshausen, ... Immunity 45 (4), 761-773, 2016 | 472 | 2016 |
Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy K Shahzad, F Bock, W Dong, H Wang, S Kopf, S Kohli, S Ranjan, J Wolter, ... Kidney international 87 (1), 74-84, 2015 | 445 | 2015 |
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRγ–Syk–Card9–dependent innate immune activation K Werninghaus, A Babiak, O Groß, C Hölscher, H Dietrich, EM Agger, ... Journal of Experimental Medicine 206 (1), 89-97, 2009 | 374 | 2009 |
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses M Ritter, O Gross, S Kays, J Ruland, F Nimmerjahn, S Saijo, J Tschopp, ... Proceedings of the National Academy of Sciences 107 (47), 20459-20464, 2010 | 297 | 2010 |
Immune modulatory effects of oncogenic KRAS in cancer S Hamarsheh, O Groß, T Brummer, R Zeiser Nature communications 11 (1), 5439, 2020 | 283 | 2020 |
The inflammasome drives GSDMD-independent secondary pyroptosis and IL-1 release in the absence of caspase-1 protease activity KS Schneider, CJ Groß, RF Dreier, BS Saller, R Mishra, O Gorka, R Heilig, ... Cell reports 21 (13), 3846-3859, 2017 | 279 | 2017 |
XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation M Yabal, N Müller, H Adler, N Knies, CJ Groß, RB Damgaard, ... Cell reports 7 (6), 1796-1808, 2014 | 269 | 2014 |
Clostridium difficile toxin–induced inflammation and intestinal injury are mediated by the inflammasome J Ng, SA Hirota, O Gross, Y Li, A Ulke–Lemee, MS Potentier, LP Schenck, ... Gastroenterology 139 (2), 542-552. e3, 2010 | 267 | 2010 |
The adaptor molecule CARD9 is essential for tuberculosis control A Dorhoi, C Desel, V Yeremeev, L Pradl, V Brinkmann, HJ Mollenkopf, ... Journal of Experimental Medicine 207 (4), 777-792, 2010 | 252 | 2010 |