DNA double-strand break repair: from mechanistic understanding to cancer treatment T Helleday, J Lo, DC van Gent, BP Engelward DNA repair 6 (7), 923-935, 2007 | 865 | 2007 |
The human gut bacterial genotoxin colibactin alkylates DNA MR Wilson, Y Jiang, PW Villalta, A Stornetta, PD Boudreau, A Carrá, ... Science 363 (6428), eaar7785, 2019 | 440 | 2019 |
Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase BP Engelward, G Weeda, MD Wyatt, JLM Broekhof, J De Wit, I Donker, ... Proceedings of the National Academy of Sciences 94 (24), 13087-13092, 1997 | 300 | 1997 |
Single cell trapping and DNA damage analysis using microwell arrays DK Wood, DM Weingeist, SN Bhatia, BP Engelward Proceedings of the National Academy of Sciences 107 (22), 10008-10013, 2010 | 298 | 2010 |
Inflammation-induced DNA damage, mutations and cancer J Kay, E Thadhani, L Samson, B Engelward DNA repair 83, 102673, 2019 | 289 | 2019 |
Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo I Koturbash, RE Rugo, CA Hendricks, J Loree, B Thibault, K Kutanzi, ... Oncogene 25 (31), 4267-4275, 2006 | 266 | 2006 |
Repair‐deficient 3‐methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation‐induced chromosome damage and cell killing. BP Engelward, A Dreslin, J Christensen, D Huszar, C Kurahara, ... The EMBO journal 15 (4), 945-952, 1996 | 236 | 1996 |
Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses RW Sobol, M Kartalou, KH Almeida, DF Joyce, BP Engelward, JK Horton, ... Journal of Biological Chemistry 278 (41), 39951-39959, 2003 | 214 | 2003 |
A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome BP Engelward, JM Allan, AJ Dreslin, JD Kelly, MM Wu, B Gold, ... Journal of Biological Chemistry 273 (9), 5412-5418, 1998 | 181 | 1998 |
Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cells P Rai, M Parrish, IJJ Tay, N Li, S Ackerman, F He, J Kwang, VT Chow, ... Proceedings of the National Academy of Sciences 112 (26), E3421-E3430, 2015 | 180 | 2015 |
DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents BJ Glassner, G Weeda, JM Allan, JLM Broekhof, NHE Carls, I Donker, ... Mutagenesis 14 (3), 339-347, 1999 | 178 | 1999 |
Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo O Kiraly, G Gong, W Olipitz, S Muthupalani, BP Engelward PLoS genetics 11 (2), e1004901, 2015 | 173 | 2015 |
High-throughput screening platform for engineered nanoparticle-mediated genotoxicity using CometChip technology C Watson, J Ge, J Cohen, G Pyrgiotakis, BP Engelward, P Demokritou ACS nano 8 (3), 2118-2133, 2014 | 165 | 2014 |
In vivo and in vitro studies on the roles of neutrophil extracellular traps during secondary pneumococcal pneumonia after primary pulmonary influenza infection A Narayana Moorthy, T Narasaraju, P Rai, B Engelward, VT Chow Frontiers in immunology 4, 39516, 2013 | 139 | 2013 |
House dust mite–induced asthma causes oxidative damage and DNA double-strand breaks in the lungs TK Chan, XY Loh, HY Peh, WNF Tan, WSD Tan, N Li, IJJ Tay, WSF Wong, ... Journal of Allergy and Clinical Immunology 138 (1), 84-96. e1, 2016 | 135 | 2016 |
Hypermutation of immunoglobulin genes in memory B cells of DNA repair–deficient mice H Jacobs, Y Fukita, GTJ Van Der Horst, J De Boer, G Weeda, J Essers, ... The Journal of experimental medicine 187 (11), 1735-1743, 1998 | 134 | 1998 |
Systems and methods for volumetric tissue scanning microscopy P So, B Engelward, T Ragan, K Bahlmann, KH Kim, L Hsu, H Huang US Patent 7,372,985, 2008 | 109 | 2008 |
Measuring DNA modifications with the comet assay: a compendium of protocols A Collins, P Møller, G Gajski, S Vodenková, A Abdulwahed, D Anderson, ... Nature protocols 18 (3), 929-989, 2023 | 103 | 2023 |
Next generation high throughput DNA damage detection platform for genotoxic compound screening P Sykora, KL Witt, P Revanna, SL Smith-Roe, J Dismukes, DG Lloyd, ... Scientific reports 8 (1), 1-20, 2018 | 96 | 2018 |
Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes B Plosky, L Samson, BP Engelward, B Gold, B Schlaen, T Millas, ... DNA repair 1 (8), 683-696, 2002 | 90 | 2002 |