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Yu-Jui Ho
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Clonal dynamics of native haematopoiesis
J Sun, A Ramos, B Chapman, JB Johnnidis, L Le, YJ Ho, A Klein, ...
Nature 514 (7522), 322-327, 2014
8602014
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
RL Frock, J Hu, RM Meyers, YJ Ho, E Kii, FW Alt
Nature biotechnology 33 (2), 179-186, 2015
7442015
Senolytic CAR T cells reverse senescence-associated pathologies
C Amor, J Feucht, J Leibold, YJ Ho, C Zhu, D Alonso-Curbelo, ...
Nature 583 (7814), 127-132, 2020
6022020
Spatial organization of the mouse genome and its role in recurrent chromosomal translocations
Y Zhang, RP McCord, YJ Ho, BR Lajoie, DG Hildebrand, AC Simon, ...
Cell 148 (5), 908-921, 2012
6002012
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells
R Chiarle, Y Zhang, RL Frock, SM Lewis, B Molinie, YJ Ho, DR Myers, ...
Cell 147 (1), 107-119, 2011
5022011
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency
J Feucht, J Sun, J Eyquem, YJ Ho, Z Zhao, J Leibold, A Dobrin, A Cabriolu, ...
Nature medicine 25 (1), 82-88, 2019
4252019
p53 represses the mevalonate pathway to mediate tumor suppression
SH Moon, CH Huang, SL Houlihan, K Regunath, WA Freed-Pastor, ...
Cell 176 (3), 564-580. e19, 2019
3182019
NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination
M Ruscetti, J Leibold, MJ Bott, M Fennell, A Kulick, NR Salgado, CC Chen, ...
Science 362 (6421), 1416-1422, 2018
2932018
Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer
M Ruscetti, JP Morris, R Mezzadra, J Russell, J Leibold, PB Romesser, ...
Cell 181 (2), 424-441. e21, 2020
2692020
A gene–environment-induced epigenetic program initiates tumorigenesis
D Alonso-Curbelo, YJ Ho, C Burdziak, JLV Maag, JP Morris IV, ...
Nature 590 (7847), 642-648, 2021
1562021
A unifying paradigm for transcriptional heterogeneity and squamous features in pancreatic ductal adenocarcinoma
A Hayashi, J Fan, R Chen, Y Ho, AP Makohon-Moore, N Lecomte, ...
Nature Cancer 1 (1), 59-74, 2020
1462020
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer
LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ...
Cancer cell 38 (2), 198-211. e8, 2020
1312020
Ordered and deterministic cancer genome evolution after p53 loss
T Baslan, JP Morris IV, Z Zhao, J Reyes, YJ Ho, KM Tsanov, J Bermeo, ...
Nature 608 (7924), 795-802, 2022
1202022
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching
J Dong, RA Panchakshari, T Zhang, Y Zhang, J Hu, SA Volpi, RM Meyers, ...
Nature 525 (7567), 134-139, 2015
1102015
Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations
YJ Ho, N Anaparthy, D Molik, G Mathew, T Aicher, A Patel, J Hicks, ...
Genome research 28 (9), 1353-1363, 2018
862018
A gain-of-function p53-mutant oncogene promotes cell fate plasticity and myeloid leukemia through the pluripotency factor FOXH1
E Loizou, A Banito, G Livshits, YJ Ho, RP Koche, FJ Sánchez-Rivera, ...
Cancer discovery 9 (7), 962-979, 2019
69*2019
Senescence rewires microenvironment sensing to facilitate antitumor immunity
HA Chen, YJ Ho, R Mezzadra, JM Adrover, R Smolkin, C Zhu, K Woess, ...
Cancer discovery 13 (2), 432-453, 2023
612023
Vitamin B6 addiction in acute myeloid leukemia
CC Chen, B Li, SE Millman, C Chen, X Li, JP Morris, A Mayle, YJ Ho, ...
Cancer Cell 37 (1), 71-84. e7, 2020
592020
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants
FJ Sánchez-Rivera, BJ Diaz, ER Kastenhuber, H Schmidt, A Katti, ...
Nature biotechnology 40 (6), 862-873, 2022
532022
Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer
WK Chatila, JK Kim, H Walch, MR Marco, CT Chen, F Wu, DM Omer, ...
Nature medicine 28 (8), 1646-1655, 2022
522022
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