Clonal dynamics of native haematopoiesis J Sun, A Ramos, B Chapman, JB Johnnidis, L Le, YJ Ho, A Klein, ... Nature 514 (7522), 322-327, 2014 | 860 | 2014 |
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases RL Frock, J Hu, RM Meyers, YJ Ho, E Kii, FW Alt Nature biotechnology 33 (2), 179-186, 2015 | 744 | 2015 |
Senolytic CAR T cells reverse senescence-associated pathologies C Amor, J Feucht, J Leibold, YJ Ho, C Zhu, D Alonso-Curbelo, ... Nature 583 (7814), 127-132, 2020 | 602 | 2020 |
Spatial organization of the mouse genome and its role in recurrent chromosomal translocations Y Zhang, RP McCord, YJ Ho, BR Lajoie, DG Hildebrand, AC Simon, ... Cell 148 (5), 908-921, 2012 | 600 | 2012 |
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells R Chiarle, Y Zhang, RL Frock, SM Lewis, B Molinie, YJ Ho, DR Myers, ... Cell 147 (1), 107-119, 2011 | 502 | 2011 |
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency J Feucht, J Sun, J Eyquem, YJ Ho, Z Zhao, J Leibold, A Dobrin, A Cabriolu, ... Nature medicine 25 (1), 82-88, 2019 | 425 | 2019 |
p53 represses the mevalonate pathway to mediate tumor suppression SH Moon, CH Huang, SL Houlihan, K Regunath, WA Freed-Pastor, ... Cell 176 (3), 564-580. e19, 2019 | 318 | 2019 |
NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination M Ruscetti, J Leibold, MJ Bott, M Fennell, A Kulick, NR Salgado, CC Chen, ... Science 362 (6421), 1416-1422, 2018 | 293 | 2018 |
Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer M Ruscetti, JP Morris, R Mezzadra, J Russell, J Leibold, PB Romesser, ... Cell 181 (2), 424-441. e21, 2020 | 269 | 2020 |
A gene–environment-induced epigenetic program initiates tumorigenesis D Alonso-Curbelo, YJ Ho, C Burdziak, JLV Maag, JP Morris IV, ... Nature 590 (7847), 642-648, 2021 | 156 | 2021 |
A unifying paradigm for transcriptional heterogeneity and squamous features in pancreatic ductal adenocarcinoma A Hayashi, J Fan, R Chen, Y Ho, AP Makohon-Moore, N Lecomte, ... Nature Cancer 1 (1), 59-74, 2020 | 146 | 2020 |
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 131 | 2020 |
Ordered and deterministic cancer genome evolution after p53 loss T Baslan, JP Morris IV, Z Zhao, J Reyes, YJ Ho, KM Tsanov, J Bermeo, ... Nature 608 (7924), 795-802, 2022 | 120 | 2022 |
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching J Dong, RA Panchakshari, T Zhang, Y Zhang, J Hu, SA Volpi, RM Meyers, ... Nature 525 (7567), 134-139, 2015 | 110 | 2015 |
Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations YJ Ho, N Anaparthy, D Molik, G Mathew, T Aicher, A Patel, J Hicks, ... Genome research 28 (9), 1353-1363, 2018 | 86 | 2018 |
A gain-of-function p53-mutant oncogene promotes cell fate plasticity and myeloid leukemia through the pluripotency factor FOXH1 E Loizou, A Banito, G Livshits, YJ Ho, RP Koche, FJ Sánchez-Rivera, ... Cancer discovery 9 (7), 962-979, 2019 | 69* | 2019 |
Senescence rewires microenvironment sensing to facilitate antitumor immunity HA Chen, YJ Ho, R Mezzadra, JM Adrover, R Smolkin, C Zhu, K Woess, ... Cancer discovery 13 (2), 432-453, 2023 | 61 | 2023 |
Vitamin B6 addiction in acute myeloid leukemia CC Chen, B Li, SE Millman, C Chen, X Li, JP Morris, A Mayle, YJ Ho, ... Cancer Cell 37 (1), 71-84. e7, 2020 | 59 | 2020 |
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants FJ Sánchez-Rivera, BJ Diaz, ER Kastenhuber, H Schmidt, A Katti, ... Nature biotechnology 40 (6), 862-873, 2022 | 53 | 2022 |
Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer WK Chatila, JK Kim, H Walch, MR Marco, CT Chen, F Wu, DM Omer, ... Nature medicine 28 (8), 1646-1655, 2022 | 52 | 2022 |