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Daniel Jesus Diaz
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Machine learning-aided engineering of hydrolases for PET depolymerization
H Lu, DJ Diaz, NJ Czarnecki, C Zhu, W Kim, R Shroff, DJ Acosta, ...
Nature 604 (7907), 662-667, 2022
2162022
Discovery of novel gain-of-function mutations guided by structure-based deep learning
R Shroff, AW Cole, DJ Diaz, BR Morrow, I Donnell, A Annapareddy, ...
ACS synthetic biology 9 (11), 2927-2935, 2020
58*2020
Improved Bst DNA Polymerase Variants Derived via a Machine Learning Approach
I Paik, PHT Ngo, R Shroff, DJ Diaz, AC Maranhao, DJF Walker, S Bhadra, ...
Biochemistry, 2021
132021
Learning the local landscape of protein structures with convolutional neural networks
AV Kulikova, DJ Diaz, JM Loy, AD Ellington, CO Wilke
Journal of Biological Physics 47 (4), 435-454, 2021
82021
GroovDB: A database of ligand-inducible transcription factors
S d’Oelsnitz, JD Love, DJ Diaz, AD Ellington
ACS Synthetic Biology 11 (10), 3534-3537, 2022
62022
Using machine learning to predict the effects and consequences of mutations in proteins
DJ Diaz, AV Kulikova, AD Ellington, CO Wilke
Current Opinion in Structural Biology 78, 102518, 2023
22023
HotProtein: A Novel Framework for Protein Thermostability Prediction and Editing
T Chen, C Gong, DJ Diaz, X Chen, JT Wells, Z Wang, A Ellington, ...
NeurIPS 2022 AI for Science: Progress and Promises, 0
2
Sequence and structure based deep learning models represent different aspects of protein biochemistry
AV Kulikova, DJ Diaz, T Chen, TJ Cole, AO Ellington, CO Wilke
bioRxiv, 2023.03. 20.533508, 2023
12023
Stability Oracle: A Structure-Based Graph-Transformer for Identifying Stabilizing Mutations
DJ Diaz, C Gong, J Ouyang-Zhang, JM Loy, J Wells, D Yang, AD Ellington, ...
bioRxiv, 2023.05. 15.540857, 2023
2023
Pushing Differential Sensing Further: The Next Steps in Design and Analysis of Bio‐Inspired Cross‐Reactive Arrays
HA Fargher, S d'Oelsnitz, DJ Diaz, EV Anslyn
Analysis & Sensing 3 (2), e202200095, 2023
2023
Synthetic microbial sensing and biosynthesis of amaryllidaceae alkaloids
S d'Oelsnitz, DJ Diaz, DJ Acosta, MW Schechter, MB Minus, JR Howard, ...
bioRxiv, 2023.04. 05.535710, 2023
2023
The Coming Congruence of Synthetic Biology and Machine Learning for Engineering Life
A Ellington, D Diaz, I Paik
2022 Astrobiology Science Conference, 2022
2022
ENGINEERING PROTEINS WITH 3D CONVOLUTIONAL NEURAL NETWORKS 8
D Diaz
2022
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Articles 1–13