Michael Houghton
Michael Houghton
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Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
QL Choo, G Kuo, AJ Weiner, LR Overby, DW Bradley, M Houghton
Science 244 (4902), 359-362, 1989
An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis
G Kuo, QL Choo, HJ Alter, GL Gitnick, AG Redeker, RH Purcell, ...
Science 244 (4902), 362-364, 1989
Binding of hepatitis C virus to CD81
P Pileri, Y Uematsu, S Campagnoli, G Galli, F Falugi, R Petracca, ...
Science 282 (5390), 938-941, 1998
Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis
HJ Alter, RH Purcell, JW Shih, JC Melpolder, M Houghton, QL Choo, ...
New England journal of medicine 321 (22), 1494-1500, 1989
A proposed system for the nomenclature of hepatitis C viral genotypes
P Simmonds, A Alberti, HJ Alter, F Bonino, DW Bradley, C Brechot, ...
Hepatology 19 (5), 1321-1324, 1994
Hepatitis C virus antibodies among risk groups in Spain
JI Esteban, L Viladomiu, A Gonzalez, M Roget, J Genesca, R Esteban, ...
The Lancet 334 (8658), 294-297, 1989
Molecular biology of the hepatitis C viruses: implications for diagnosis, development and control of viral disease
M Houghton, A Weiner, J Han, G Kuo, QL Choo
Hepatology 14 (2), 381-388, 1991
Analysis of a successful immune response against hepatitis C virus
S Cooper, AL Erickson, EJ Adams, J Kansopon, AJ Weiner, DY Chien, ...
Immunity 10 (4), 439-449, 1999
Detection of hepatitis C viral sequences in non-A, non-B hepatitis
AJ Weiner, G Kuo, C Lee, J Rosenblatt, QL Choo, M Houghton, ...
The Lancet 335 (8680), 1-3, 1990
Structure, sequence and expression of the hepatitis delta (δ) viral genome
KS Wang, QL Choo, AJ Weiner, JH Ou, RC Najarian, RM Thayer, ...
Nature 323 (6088), 508-514, 1986
Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response.
G Missale, R Bertoni, V Lamonaca, A Valli, M Massari, C Mori, MG Rumi, ...
The Journal of clinical investigation 98 (3), 706-714, 1996
Prevalence of antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma
M Colombo, QL Choo, E Del Ninno, N Dioguardi, G Kuo, MF Donato, ...
The Lancet 334 (8670), 1006-1008, 1989
Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins
AJ Weiner, MJ Brauer, J Rosenblatt, KH Richman, J Tung, K Crawford, ...
Virology 180 (2), 842-848, 1991
Memory CD8+ T Cells Are Required for Protection from Persistent Hepatitis C Virus Infection
NH Shoukry, A Grakoui, M Houghton, DY Chien, J Ghrayeb, KA Reimann, ...
The Journal of experimental medicine 197 (12), 1645-1655, 2003
Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay
CL Van der Poel, HW Reesink, JJP van Boven, HTM Cuypers, I Winkel, ...
The Lancet 337 (8737), 317-319, 1991
Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5'untranslated region and poly (A) tails at the 3'end.
JH Han, V Shyamala, KH Richman, MJ Brauer, B Irvine, MS Urdea, ...
Proceedings of the National Academy of Sciences 88 (5), 1711-1715, 1991
Intrahepatic cytotoxic T lymphocytes specific for hepatitis C virus in persons with chronic hepatitis.
MJ Koziel, D Dudley, JT Wong, J Dienstag, M Houghton, R Ralston, ...
Journal of immunology (Baltimore, Md.: 1950) 149 (10), 3339-3344, 1992
Hepatitis C virus: the major causative agent of viral non-A, non-B hepatitis
QL Choo, AJ Weiner, LR Overby, G Kuo, M Houghton, DW Bradley
British medical bulletin 46 (2), 423-441, 1990
The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes
AL Erickson, Y Kimura, S Igarashi, J Eichelberger, M Houghton, J Sidney, ...
Immunity 15 (6), 883-895, 2001
A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.
D Rosa, S Campagnoli, C Moretto, E Guenzi, L Cousens, M Chin, C Dong, ...
Proceedings of the National Academy of Sciences 93 (5), 1759-1763, 1996
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