Multiplex assessment of protein variant abundance by massively parallel sequencing KA Matreyek, LM Starita, JJ Stephany, B Martin, MA Chiasson, VE Gray, ... Nature genetics 50 (6), 874-882, 2018 | 435 | 2018 |
Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity KA Matreyek, SS Yücel, X Li, A Engelman PLoS pathogens 9 (10), e1003693, 2013 | 317 | 2013 |
The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid KA Matreyek, A Engelman Journal of virology 85 (15), 7818-7827, 2011 | 270 | 2011 |
N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entry HC Aguilar, KA Matreyek, CM Filone, ST Hashimi, EL Levroney, ... Journal of virology 80 (10), 4878-4889, 2006 | 247 | 2006 |
On the design of CRISPR-based single-cell molecular screens AJ Hill, JL McFaline-Figueroa, LM Starita, MJ Gasperini, KA Matreyek, ... Nature methods 15 (4), 271-274, 2018 | 233 | 2018 |
The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase L Krishnan, KA Matreyek, I Oztop, K Lee, CH Tipper, X Li, MJ Dar, ... Journal of virology 84 (1), 397-406, 2010 | 229 | 2010 |
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution TN Starr, AJ Greaney, WW Hannon, AN Loes, K Hauser, JR Dillen, E Ferri, ... Science 377 (6604), 420-424, 2022 | 225 | 2022 |
Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes KA Matreyek, A Engelman Viruses 5 (10), 2483-2511, 2013 | 175* | 2013 |
A platform for functional assessment of large variant libraries in mammalian cells KA Matreyek, JJ Stephany, DM Fowler Nucleic acids research 45 (11), e102-e102, 2017 | 164 | 2017 |
Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration Y Koh, X Wu, AL Ferris, KA Matreyek, SJ Smith, KE Lee, ... Journal of virology 87 (1), 648-658, 2013 | 153 | 2013 |
An improved platform for functional assessment of large protein libraries in mammalian cells KA Matreyek, JJ Stephany, MA Chiasson, N Hasle, DM Fowler Nucleic acids research 48 (1), e1-e1, 2020 | 147 | 2020 |
Structural insight into HIV-1 restriction by MxB JL Fribourgh, HC Nguyen, KA Matreyek, FJD Alvarez, BJ Summers, ... Cell host & microbe 16 (5), 627-638, 2014 | 142 | 2014 |
Polybasic KKR motif in the cytoplasmic tail of Nipah virus fusion protein modulates membrane fusion by inside-out signaling HC Aguilar, KA Matreyek, DY Choi, CM Filone, S Young, B Lee Journal of virology 81 (9), 4520-4532, 2007 | 125 | 2007 |
Host and viral determinants for MxB restriction of HIV-1 infection KA Matreyek, W Wang, E Serrao, PK Singh, HL Levin, A Engelman Retrovirology 11, 1-20, 2014 | 120 | 2014 |
Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity CC Suiter, T Moriyama, KA Matreyek, W Yang, ER Scaletti, R Nishii, ... Proceedings of the National Academy of Sciences 117 (10), 5394-5401, 2020 | 117 | 2020 |
MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses A Bruchez, K Sha, J Johnson, L Chen, C Stefani, H McConnell, ... Science 370 (6513), 241-247, 2020 | 104 | 2020 |
Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact MA Chiasson, NJ Rollins, JJ Stephany, KA Sitko, KA Matreyek, M Verby, ... elife 9, e58026, 2020 | 75 | 2020 |
Extracellular vesicles carry SARS‐CoV‐2 spike protein and serve as decoys for neutralizing antibodies Z Troyer, N Alhusaini, CO Tabler, T Sweet, KIL de Carvalho, DM Schlatzer, ... Journal of Extracellular Vesicles 10 (8), e12112, 2021 | 70 | 2021 |
High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11. 1 KA Kozek, AM Glazer, CA Ng, D Blackwell, CL Egly, LR Vanags, M Blair, ... Heart rhythm 17 (12), 2180-2189, 2020 | 54 | 2020 |
Differential sensitivities of retroviruses to integrase strand transfer inhibitors Y Koh, KA Matreyek, A Engelman Journal of virology 85 (7), 3677-3682, 2011 | 44 | 2011 |