Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ... Science 344 (6190), 1396-1401, 2014 | 4691 | 2014 |
An integrative model of cellular states, plasticity, and genetics for glioblastoma C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ... Cell 178 (4), 835-849. e21, 2019 | 1977 | 2019 |
Insulator dysfunction and oncogene activation in IDH mutant gliomas WA Flavahan, Y Drier, BB Liau, SM Gillespie, AS Venteicher, ... Nature 529 (7584), 110-114, 2016 | 1353 | 2016 |
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial DB Keskin, AJ Anandappa, J Sun, I Tirosh, ND Mathewson, S Li, ... Nature 565 (7738), 234-239, 2019 | 1240 | 2019 |
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ... Nature 539 (7628), 309-313, 2016 | 1084 | 2016 |
Electrical and synaptic integration of glioma into neural circuits HS Venkatesh, W Morishita, AC Geraghty, D Silverbush, SM Gillespie, ... Nature 573 (7775), 539-545, 2019 | 967 | 2019 |
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells ML Suvā, E Rheinbay, SM Gillespie, AP Patel, H Wakimoto, SD Rabkin, ... Cell 157 (3), 580-594, 2014 | 965 | 2014 |
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ... Science 355 (6332), eaai8478, 2017 | 924 | 2017 |
Epigenetic reprogramming in cancer ML Suvā, N Riggi, BE Bernstein Science 339 (6127), 1567-1570, 2013 | 862 | 2013 |
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ... Science 360 (6386), 331-335, 2018 | 606 | 2018 |
EZH2 is essential for glioblastoma cancer stem cell maintenance ML Suvā, N Riggi, M Janiszewska, I Radovanovic, P Provero, JC Stehle, ... Cancer research 69 (24), 9211-9218, 2009 | 549 | 2009 |
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors RL Flynn, KE Cox, M Jeitany, H Wakimoto, AR Bryll, NJ Ganem, F Bersani, ... Science 347 (6219), 273-277, 2015 | 537 | 2015 |
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ... Nature medicine 26 (5), 792-802, 2020 | 527 | 2020 |
Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ... Cell stem cell 20 (2), 233-246. e7, 2017 | 516 | 2017 |
Malarial hemozoin is a Nalp3 inflammasome activating danger signal C Dostert, G Guarda, JF Romero, P Menu, O Gross, A Tardivel, ML Suva, ... PloS one 4 (8), e6510, 2009 | 480 | 2009 |
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate L Bunse, S Pusch, T Bunse, F Sahm, K Sanghvi, M Friedrich, D Alansary, ... Nature medicine 24 (8), 1192-1203, 2018 | 472 | 2018 |
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells M Janiszewska, ML Suvā, N Riggi, RH Houtkooper, J Auwerx, ... Genes & development 26 (17), 1926-1944, 2012 | 472 | 2012 |
Development of Ewing's sarcoma from primary bone marrow–derived mesenchymal progenitor cells N Riggi, L Cironi, P Provero, ML Suvā, K Kaloulis, C Garcia-Echeverria, ... Cancer research 65 (24), 11459-11468, 2005 | 451 | 2005 |
EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma N Riggi, B Knoechel, SM Gillespie, E Rheinbay, G Boulay, ML Suvā, ... Cancer cell 26 (5), 668-681, 2014 | 444 | 2014 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 441 | 2020 |