PsN-Toolkit—a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM L Lindbom, P Pihlgren, N Jonsson Computer methods and programs in biomedicine 79 (3), 241-257, 2005 | 1163 | 2005 |
Xpose—an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM EN Jonsson, MO Karlsson Computer methods and programs in biomedicine 58 (1), 51-64, 1998 | 1118 | 1998 |
Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming L Lindbom, J Ribbing, EN Jonsson Computer methods and programs in biomedicine 75 (2), 85-94, 2004 | 751 | 2004 |
Assessment of actual significance levels for covariate effects in NONMEM U Wählby, EN Jonsson, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 28, 231-252, 2001 | 349 | 2001 |
Automated covariate model building within NONMEM EN Jonsson, MO Karlsson Pharmaceutical research 15, 1463-1468, 1998 | 324 | 1998 |
Comparison of stepwise covariate model building strategies in population pharmacokinetic-pharmacodynamic analysis U Wählby, EN Jonsson, MO Karlsson Aaps Pharmsci 4, 68-79, 2002 | 234 | 2002 |
Assumption testing in population pharmacokinetic models: illustrated with an analysis of moxonidine data from congestive heart failure patients MO Karlsson, EN Jonsson, CG Wiltse, JR Wade Journal of pharmacokinetics and biopharmaceutics 26, 207-246, 1998 | 192 | 1998 |
Power, selection bias and predictive performance of the population pharmacokinetic covariate model J Ribbing, E Niclas Jonsson Journal of pharmacokinetics and pharmacodynamics 31, 109-134, 2004 | 176 | 2004 |
A PK–PD Model for Predicting the Impact of Age, CYP2C9, and VKORC1 Genotype on Individualization of Warfarin Therapy AK Hamberg, ML Dahl, M Barban, MG Scordo, M Wadelius, V Pengo, ... Clinical Pharmacology & Therapeutics 81 (4), 529-538, 2007 | 175 | 2007 |
A comprehensive hepatitis C viral kinetic model explaining cure E Snoeck, P Chanu, M Lavielle, P Jacqmin, EN Jonsson, K Jorga, ... Clinical Pharmacology & Therapeutics 87 (6), 706-713, 2010 | 152 | 2010 |
Brain distribution of cetirizine enantiomers: comparison of three different tissue-to-plasma partition coefficients: Kp, Kp, u, and Kp, uu A Gupta, P Chatelain, R Massingham, EN Jonsson, ... Drug metabolism and disposition 34 (2), 318-323, 2006 | 145 | 2006 |
Non-linear mixed-effects models with stochastic differential equations: implementation of an estimation algorithm RV Overgaard, N Jonsson, CW Tornøe, H Madsen Journal of pharmacokinetics and pharmacodynamics 32, 85-107, 2005 | 130 | 2005 |
Morphine blood-brain barrier transport is influenced by probenecid co-administration K Tunblad, EN Jonsson, M Hammarlund-Udenaes Pharmaceutical research 20, 618-623, 2003 | 112 | 2003 |
Comparison of some practical sampling strategies for population pharmacokinetic studies EN Jonsson, JR Wade, MO Karlsson Journal of pharmacokinetics and biopharmaceutics 24, 245-263, 1996 | 107 | 1996 |
Stochastic differential equations in NONMEM®: implementation, application, and comparison with ordinary differential equations CW Tornøe, RV Overgaard, H Agersø, HA Nielsen, H Madsen, ... Pharmaceutical research 22, 1247-1258, 2005 | 104 | 2005 |
The lasso—a novel method for predictive covariate model building in nonlinear mixed effects models J Ribbing, J Nyberg, O Caster, EN Jonsson Journal of pharmacokinetics and pharmacodynamics 34, 485-517, 2007 | 99 | 2007 |
Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients M Sandström, MO Karlsson, P Ljungman, Z Hassan, EN Jonsson, ... Bone marrow transplantation 28 (7), 657-664, 2001 | 87 | 2001 |
Assessment of type I error rates for the statistical sub-model in NONMEM U Wählby, MR Bouw, EN Jonsson, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 29, 251-269, 2002 | 78 | 2002 |
A pharmacokinetic‐pharmacodynamic model for the quantitative prediction of dofetilide clinical QT prolongation from human ether‐a‐go‐go‐related gene current inhibition data DM Jonker, LA Kenna, D Leishman, R Wallis, PA Milligan, EN Jonsson Clinical pharmacology & therapeutics 77 (6), 572-582, 2005 | 77 | 2005 |
Nonlinearity detection: advantages of nonlinear mixed-effects modeling EN Jonsson, MO Karlsson, JR Wade Aaps Pharmsci 2, 114-123, 2000 | 71 | 2000 |