Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation N Kubo, H Ishii, X Xiong, S Bianco, F Meitinger, R Hu, JD Hocker, ... Nature structural & molecular biology 28 (2), 152-161, 2021 | 238 | 2021 |
CTCF mediates dosage-and sequence-context-dependent transcriptional insulation by forming local chromatin domains H Huang, Q Zhu, A Jussila, Y Han, B Bintu, C Kern, M Conte, Y Zhang, ... Nature genetics 53 (7), 1064-1074, 2021 | 125 | 2021 |
Polymer physics indicates chromatin folding variability across single-cells results from state degeneracy in phase separation M Conte, L Fiorillo, S Bianco, AM Chiariello, A Esposito, M Nicodemi Nature communications 11 (1), 3289, 2020 | 100 | 2020 |
Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding M Conte, E Irani, AM Chiariello, A Abraham, S Bianco, A Esposito, ... Nature Communications 13 (1), 4070, 2022 | 56 | 2022 |
Comparison of the Hi-C, GAM and SPRITE methods using polymer models of chromatin L Fiorillo, F Musella, M Conte, R Kempfer, AM Chiariello, S Bianco, ... Nature methods 18 (5), 482-490, 2021 | 49 | 2021 |
A dynamic folded hairpin conformation is associated with α-globin activation in erythroid cells AM Chiariello, S Bianco, AM Oudelaar, A Esposito, C Annunziatella, ... Cell Reports 30 (7), 2125-2135. e5, 2020 | 38 | 2020 |
Computational approaches from polymer physics to investigate chromatin folding S Bianco, AM Chiariello, M Conte, A Esposito, L Fiorillo, F Musella, ... Current opinion in cell biology 64, 10-17, 2020 | 33 | 2020 |
Polymer physics reveals a combinatorial code linking 3D chromatin architecture to 1D chromatin states A Esposito, S Bianco, AM Chiariello, A Abraham, L Fiorillo, M Conte, ... Cell Reports 38 (13), 2022 | 23 | 2022 |
Modeling single-molecule conformations of the HoxD region in mouse embryonic stem and cortical neuronal cells S Bianco, C Annunziatella, G Andrey, AM Chiariello, A Esposito, L Fiorillo, ... Cell reports 28 (6), 1574-1583. e4, 2019 | 22 | 2019 |
A modern challenge of polymer physics: novel ways to study, interpret, and reconstruct chromatin structure L Fiorillo, S Bianco, A Esposito, M Conte, R Sciarretta, F Musella, ... Wiley Interdisciplinary Reviews: Computational Molecular Science 10 (4), e1454, 2020 | 21 | 2020 |
Higher-order chromosome structures investigated by polymer physics in cellular morphogenesis and differentiation A Esposito, AM Chiariello, M Conte, L Fiorillo, F Musella, R Sciarretta, ... Journal of molecular biology 432 (3), 701-711, 2020 | 14 | 2020 |
Inference of chromosome 3D structures from GAM data by a physics computational approach L Fiorillo, S Bianco, AM Chiariello, M Barbieri, A Esposito, ... Methods 181, 70-79, 2020 | 13 | 2020 |
Physical mechanisms of chromatin spatial organization AM Chiariello, S Bianco, A Esposito, L Fiorillo, M Conte, E Irani, F Musella, ... The FEBS Journal 289 (5), 1180-1190, 2022 | 12 | 2022 |
Divergent transcription of the Nkx2-5 locus generates two enhancer RNAs with opposing functions I Salamon, S Serio, S Bianco, C Pagiatakis, S Crasto, AM Chiariello, ... Iscience 23 (9), 2020 | 12 | 2020 |
CTCF promotes long-range enhancer-promoter interactions and lineage-specific gene expression in mammalian cells N Kubo, H Ishii, X Xiong, S Bianco, F Meitinger, R Hu, JD Hocker, ... BioRxiv, 2020.03. 21.001693, 2020 | 12 | 2020 |
3DGenBench: a web-server to benchmark computational models for 3D Genomics Nucleic Acids Research 50 (W1), W4-W12, 2022 | 10 | 2022 |
The physics of DNA folding: polymer models and phase-separation A Esposito, A Abraham, M Conte, F Vercellone, A Prisco, S Bianco, ... Polymers 14 (9), 1918, 2022 | 10 | 2022 |
Polymer models are a versatile tool to study chromatin 3D organization A Esposito, S Bianco, L Fiorillo, M Conte, A Abraham, F Musella, ... Biochemical Society Transactions 49 (4), 1675-1684, 2021 | 10 | 2021 |
Comparison of the Hi-C, GAM and SPRITE methods by use of polymer models of chromatin L Fiorillo, F Musella, R Kempfer, AM Chiariello, S Bianco, A Kukalev, ... BioRxiv, 2020.04. 24.059915, 2020 | 8 | 2020 |
Efficient computational implementation of polymer physics models to explore chromatin structure M Conte, A Esposito, L Fiorillo, R Campanile, C Annunziatella, A Corrado, ... International Journal of Parallel, Emergent and Distributed Systems 37 (1 …, 2022 | 7 | 2022 |