Carrier testing for severe childhood recessive diseases by next-generation sequencing CJ Bell, DL Dinwiddie, NA Miller, SL Hateley, EE Ganusova, J Mudge, ... Science translational medicine 3 (65), 65ra4-65ra4, 2011 | 864 | 2011 |
An integrated clinico-metabolomic model improves prediction of death in sepsis RJ Langley, EL Tsalik, JC Velkinburgh, SW Glickman, BJ Rice, C Wang, ... Science translational medicine 5 (195), 195ra95-195ra95, 2013 | 501 | 2013 |
An integrated transcriptome atlas of the crop model Glycine max, and its use in comparative analyses in plants M Libault, A Farmer, T Joshi, K Takahashi, RJ Langley, LD Franklin, J He, ... The Plant Journal 63 (1), 86-99, 2010 | 440 | 2010 |
Complete Transcriptome of the Soybean Root Hair Cell, a Single-Cell Model, and Its Alteration in Response to Bradyrhizobium japonicum Infection M Libault, A Farmer, L Brechenmacher, J Drnevich, RJ Langley, DD Bilgin, ... Plant physiology 152 (2), 541-552, 2010 | 329 | 2010 |
Unsupervised analysis of transcriptomics in bacterial sepsis across multiple datasets reveals three robust clusters TE Sweeney, TD Azad, M Donato, WA Haynes, TM Perumal, R Henao, ... Critical care medicine 46 (6), 915-925, 2018 | 269 | 2018 |
Host gene expression classifiers diagnose acute respiratory illness etiology EL Tsalik, R Henao, M Nichols, T Burke, ER Ko, MT McClain, LL Hudson, ... Science translational medicine 8 (322), 322ra11-322ra11, 2016 | 253 | 2016 |
Discriminative value of inflammatory biomarkers for suspected sepsis EL Tsalik, LB Jaggers, SW Glickman, RJ Langley, JC Van Velkinburgh, ... The Journal of emergency medicine 43 (1), 97-106, 2012 | 224 | 2012 |
T cells express α7-nicotinic acetylcholine receptor subunits that require a functional TCR and leukocyte-specific protein tyrosine kinase for nicotine-induced Ca2+ response S Razani-Boroujerdi, RT Boyd, MI Dávila-García, JS Nandi, NC Mishra, ... The Journal of Immunology 179 (5), 2889-2898, 2007 | 215 | 2007 |
A community approach to mortality prediction in sepsis via gene expression analysis TE Sweeney, TM Perumal, R Henao, M Nichols, JA Howrylak, AM Choi, ... Nature communications 9 (1), 694, 2018 | 198 | 2018 |
Metabolomic derangements are associated with mortality in critically ill adult patients AJ Rogers, M McGeachie, RM Baron, L Gazourian, JA Haspel, ... PloS one 9 (1), e87538, 2014 | 179 | 2014 |
Multiplex PCR to diagnose bloodstream infections in patients admitted from the emergency department with sepsis EL Tsalik, D Jones, B Nicholson, L Waring, O Liesenfeld, LP Park, ... Journal of clinical microbiology 48 (1), 26-33, 2010 | 178 | 2010 |
Disease progression in hemodynamically stable patients presenting to the emergency department with sepsis SW Glickman, CB Cairns, RM Otero, CW Woods, EL Tsalik, RJ Langley, ... Academic Emergency Medicine 17 (4), 383-390, 2010 | 177 | 2010 |
Meiosis-specific gene discovery in plants: RNA-Seq applied to isolated Arabidopsis male meiocytes C Chen, AD Farmer, RJ Langley, J Mudge, JA Crow, GD May, J Huntley, ... BMC plant biology 10, 1-14, 2010 | 147 | 2010 |
Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum J Mudge, NA Miller, I Khrebtukova, IE Lindquist, GD May, JJ Huntley, ... PloS one 3 (11), e3625, 2008 | 147 | 2008 |
Immunosuppressive and anti-inflammatory effects of nicotine administered by patch in an animal model R Kalra, SP Singh, JC Pena-Philippides, RJ Langley, ... Clinical and Vaccine Immunology 11 (3), 563-568, 2004 | 122 | 2004 |
Integrative “omic” analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response syndromes RJ Langley, JL Tipper, S Bruse, RM Baron, EL Tsalik, J Huntley, ... American journal of respiratory and critical care medicine 190 (4), 445-455, 2014 | 111 | 2014 |
Prenatal cigarette smoke decreases lung cAMP and increases airway hyperresponsiveness SP Singh, EG Barrett, R Kalra, S Razani-Boroujerdi, RJ Langley, V Kurup, ... American journal of respiratory and critical care medicine 168 (3), 342-347, 2003 | 108 | 2003 |
Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens NC Mishra, J Rir-Sima-Ah, RJ Langley, SP Singh, JC Peña-Philippides, ... The Journal of Immunology 180 (11), 7655-7663, 2008 | 106 | 2008 |
An integrated transcriptome and expressed variant analysis of sepsis survival and death EL Tsalik, RJ Langley, DL Dinwiddie, NA Miller, B Yoo, ... Genome medicine 6, 1-15, 2014 | 103 | 2014 |
Chronic nicotine inhibits inflammation and promotes influenza infection S Razani-Boroujerdi, SP Singh, C Knall, FF Hahn, JC Peņa-Philippides, ... Cellular immunology 230 (1), 1-9, 2004 | 103 | 2004 |