Tyler Jacks
Tyler Jacks
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Cited by
Cited by
MicroRNA expression profiles classify human cancers
J Lu, G Getz, EA Miska, E Alvarez-Saavedra, J Lamb, D Peck, ...
nature 435 (7043), 834-838, 2005
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
M Guttman, I Amit, M Garber, C French, MF Lin, D Feldser, M Huarte, ...
Nature 458 (7235), 223-227, 2009
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
MB Kastan, Q Zhan, WS El-Deiry, F Carrier, T Jacks, WV Walsh, ...
Cell 71 (4), 587-597, 1992
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
SW Lowe, HE Ruley, T Jacks, DE Housman
Cell 74 (6), 957-967, 1993
p53 is required for radiation-induced apoptosis in mouse thymocytes
SW Lowe, EM Schmitt, SW Smith, BA Osborne, T Jacks
Nature 362 (6423), 847-849, 1993
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ...
Nature 462 (7269), 108-112, 2009
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
TG Graeber, C Osmanian, T Jacks, DE Housman, CJ Koch, SW Lowe, ...
nature 379 (6560), 88-91, 1996
Identification of bronchioalveolar stem cells in normal lung and lung cancer
CFB Kim, EL Jackson, AE Woolfenden, S Lawrence, I Babar, S Vogel, ...
Cell 121 (6), 823-835, 2005
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani, EF Petricoin, A Maitra, V Rajapakse, C King, MA Jacobetz, ...
Cancer cell 4 (6), 437-450, 2003
Tumor spectrum analysis in p53-mutant mice
T Jacks, L Remington, BO Williams, EM Schmitt, S Halachmi, RT Bronson, ...
Current biology 4 (1), 1-7, 1994
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
M Huarte, M Guttman, D Feldser, M Garber, MJ Koziol, ...
Cell 142 (3), 409-419, 2010
Effects of an Rb mutation in the mouse
T Jacks, A Fazeli, EM Schmitt, RT Bronson, MA Goodell, RA Weinberg
Nature 359 (6393), 295-300, 1992
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
EL Jackson, N Willis, K Mercer, RT Bronson, D Crowley, R Montoya, ...
Genes & development 15 (24), 3243-3248, 2001
Restoration of p53 function leads to tumour regression in vivo
A Ventura, DG Kirsch, ME McLaughlin, DA Tuveson, J Grimm, L Lintault, ...
Nature 445 (7128), 661-665, 2007
p53 status and the efficacy of cancer therapy in vivo
SW Lowe, S Bodis, A McClatchey, L Remington, HE Ruley, DE Fisher, ...
Science 266 (5186), 807-810, 1994
Targeted deletion reveals essential and overlapping functions of the miR-17∼ 92 family of miRNA clusters
A Ventura, AG Young, MM Winslow, L Lintault, A Meissner, SJ Erkeland, ...
Cell 132 (5), 875-886, 2008
Sunburn and p53 in the onset of skin cancer
A Ziegler, AS Jonason, DJ Leffellt, JA Simon, HW Sharma, J Kimmelman, ...
Nature 372 (6508), 773-776, 1994
Impaired microRNA processing enhances cellular transformation and tumorigenesis
MS Kumar, J Lu, KL Mercer, TR Golub, T Jacks
Nature genetics 39 (5), 673-677, 2007
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
LR Livingstone, A White, J Sprouse, E Livanos, T Jacks, TD Tlsty
Cell 70 (6), 923-935, 1992
Radiation-induced cell cycle arrest compromised by p21 deficiency
J Brugarolas, C Chandrasekaran, JI Gordon, D Beach, T Jacks, ...
Nature 377 (6549), 552-557, 1995
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