| Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury S Lin, EM Nascimento, CR Gajera, L Chen, P Neuhöfer, A Garbuzov, ... Nature 556 (7700), 244, 2018 | 244 | 2018 |
| Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling L Chen, Y Cai, J Jin, L Florens, SK Swanson, MP Washburn, ... Journal of Biological Chemistry 286 (13), 11283-11289, 2011 | 118 | 2011 |
| An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1 L Chen, CM Roake, A Freund, PJ Batista, S Tian, YA Yin, CR Gajera, ... Cell 174, 1-13, 2018 | 84 | 2018 |
| Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex L Chen, RC Conaway, JW Conaway Proceedings of the National Academy of Sciences 110 (51), 20497-20502, 2013 | 57 | 2013 |
| Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease CM Roake, L Chen, AL Chakravarthy, JE Ferrell Jr, GD Raffa, SE Artandi Molecular Cell 64, 688-700, 2019 | 56 | 2019 |
| Loss of human TGS1 hypermethylase promotes increased telomerase RNA and telomere elongation L Chen, CM Roake, A Galati, F Bavasso, E Micheli, I Saggio, S Schoeftner, ... Cell Reports 30, 1358-1372, 2020 | 44 | 2020 |
| Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus S Vaidyanathan, R Baik, L Chen, DT Bravo, CJ Suarez, SM Abazari, ... Molecular Therapy 30 (1), 223-237, 2022 | 39 | 2022 |
| Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α D Sela, JJ Conkright, L Chen, J Gilmore, MP Washburn, L Florens, ... Journal of Biological Chemistry 288 (36), 26179-26187, 2013 | 38 | 2013 |
| Cholesterol-dependent and-independent CD40 internalization and signaling activation in cardiovascular endothelial cells J Chen, L Chen, G Wang, H Tang Arteriosclerosis, thrombosis, and vascular biology 27 (9), 2005-2013, 2007 | 35 | 2007 |
| Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif L Wang, O Limbo, J Fei, L Chen, B Kim, J Luo, J Chong, RC Conaway, ... Proceedings of the National Academy of Sciences 111 (52), 18566-18571, 2014 | 27 | 2014 |
| Endoplasmic Reticulum Stress-responsive Transcription Factor ATF6α Directs Recruitment of the Mediator of RNA Polymerase II Transcription and Multiple Histone Acetyltransferase … D Sela, L Chen, S Martin-Brown, MP Washburn, L Florens, JW Conaway, ... Journal of Biological Chemistry 287 (27), 23035-23045, 2012 | 26 | 2012 |
| A novel DDB2 mutation causes defective recognition of UV-induced DNA damages and prevalent equine squamous cell carcinoma L Chen, RR Bellone, Y Wang, M Singer-Berk, K Sugasawa, JM Ford, ... DNA repair 97, 103022, 2021 | 12 | 2021 |
| Generation and purification of human INO80 chromatin remodeling complexes and subcomplexes L Chen, SK Ooi, RC Conaway, JW Conaway JoVE (Journal of Visualized Experiments), e51720, 2014 | 9 | 2014 |
| Targeting DHX9 triggers tumor-intrinsic interferon response and replication stress in Small Cell Lung Cancer T Murayama, J Nakayama, X Jiang, K Miyata, AD Morris, KQ Cai, ... Cancer Discovery 14 (3), 468-491, 2024 | 6 | 2024 |
| Analysis of RNA conformation in endogenously assembled RNPs by icSHAPE L Chen, HY Chang, SE Artandi STAR Protocols 2 (2), 100477, 2021 | 4 | 2021 |
| TGS1 impacts snRNA 3′-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration L Chen, CM Roake, P Maccallini, F Bavasso, R Dehghannasiri, ... Nucleic Acids Research 50 (21), 12400-12424, 2022 | 3 | 2022 |
| The S‐adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening A Galati, L Scatolini, E Micheli, F Bavasso, A Cicconi, P Maccallini, ... FEBS letters 596 (1), 42-52, 2022 | 3 | 2022 |
| Biochemical assays for analyzing activities of ATP-dependent chromatin remodeling enzymes L Chen, SK Ooi, JW Conaway, RC Conaway JoVE (Journal of Visualized Experiments), e51721, 2014 | 3 | 2014 |
| TGS1 controls snRNA 3’ end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo L Chen, CM Roake, P Maccallini, B F, R Dehghannasiri, S P, ... bioRxiv 356782 (doi.org/10.1101/2020.10.27.356782), 2020 | 2 | 2020 |
| The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats A Huda, H Arakawa, G Mazzucco, M Galli, V Petrocelli, S Casola, L Chen, ... Science Advances 9 (12), eadf2011, 2023 | | 2023 |
Shengda LinStanford UniversityVerified email at stanford.edu
