| BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance R Drost, P Bouwman, S Rottenberg, U Boon, E Schut, S Klarenbeek, ... Cancer cell 20 (6), 797-809, 2011 | 267 | 2011 |
| Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland S Annunziato, SM Kas, M Nethe, H Yücel, J Del Bravo, C Pritchard, RB Ali, ... Genes & development 30 (12), 1470-1480, 2016 | 129 | 2016 |
| Expression of receptors for luteinizing hormone, gastric-inhibitory polypeptide, and vasopressin in normal adrenal glands and cortisol-secreting adrenocortical tumors in dogs S Galac, VJ Kars, S Klarenbeek, KJ Teerds, JA Mol, HS Kooistra Domestic animal endocrinology 39 (1), 63-75, 2010 | 118 | 2010 |
| BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1 R Drost, KK Dhillon, H Van Der Gulden, I Van Der Heijden, I Brandsma, ... The Journal of clinical investigation 126 (8), 2903-2918, 2016 | 110 | 2016 |
| Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma SM Kas, JR De Ruiter, K Schipper, S Annunziato, E Schut, S Klarenbeek, ... Nature genetics 49 (8), 1219-1230, 2017 | 78 | 2017 |
| A Preclinical Mouse Model of Invasive Lobular Breast Cancer MetastasisA Preclinical Mouse Model of Breast Cancer Metastasis CW Doornebal, S Klarenbeek, TM Braumuller, CN Klijn, M Ciampricotti, ... Cancer research 73 (1), 353-363, 2013 | 70 | 2013 |
| XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data RJC Kluin, K Kemper, T Kuilman, JR de Ruiter, V Iyer, JV Forment, ... BMC bioinformatics 19 (1), 1-15, 2018 | 62 | 2018 |
| PTEN loss in E-cadherin-deficient mouse mammary epithelial cells rescues apoptosis and results in development of classical invasive lobular carcinoma MC Boelens, M Nethe, S Klarenbeek, JR de Ruiter, E Schut, N Bonzanni, ... Cell reports 16 (8), 2087-2101, 2016 | 56 | 2016 |
| Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours JM Fernandes Neto, E Nadal, E Bosdriesz, SN Ooft, L Farre, C McLean, ... Nature communications 11 (1), 3157, 2020 | 53 | 2020 |
| Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor SignalingLoss of p120 Leads to … RCJ Schackmann, S Klarenbeek, EJ Vlug, S Stelloo, M Van Amersfoort, ... Cancer research 73 (15), 4937-4949, 2013 | 52 | 2013 |
| Cross-species comparison of aCGH data from mouse and human BRCA1-and BRCA2-mutated breast cancers H Holstege, E van Beers, A Velds, X Liu, SA Joosse, S Klarenbeek, ... BMC cancer 10 (1), 1-16, 2010 | 45 | 2010 |
| Effect of growth-promoting 17β-estradiol, 19-nortestosterone and dexamethasone on circulating levels of nine potential biomarker candidates in veal calves G Cacciatore, SWF Eisenberg, C Situ, MH Mooney, P Delahaut, ... Analytica chimica acta 637 (1-2), 351-359, 2009 | 42 | 2009 |
| Genetically engineered mouse models of PI3K signaling in breast cancer S Klarenbeek, MH van Miltenburg, J Jonkers Molecular oncology 7 (2), 146-164, 2013 | 37 | 2013 |
| Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547Resistance Mechanisms to FGFR-Targeted Therapy in ILC SM Kas, JR De Ruiter, K Schipper, E Schut, L Bombardelli, E Wientjens, ... Cancer Research 78 (19), 5668-5679, 2018 | 29 | 2018 |
| Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma H Vlaming, CM McLean, T Korthout, MF Alemdehy, S Hendriks, C Lancini, ... The EMBO Journal 38 (14), e101564, 2019 | 26 | 2019 |
| Somatic structural rearrangements in genetically engineered mouse mammary tumors I Varela, C Klijn, PJ Stephens, LJ Mudie, L Stebbings, D Galappaththige, ... Genome biology 11 (10), 1-12, 2010 | 26 | 2010 |
| Influence of 17β-oestradiol, nortestosterone and dexamethasone on the adaptive immune response in veal calves SWF Eisenberg, G Cacciatore, S Klarenbeek, AA Bergwerff, AP Koets Research in veterinary science 84 (2), 199-205, 2008 | 18 | 2008 |
| Reducing chloride conductance prevents hyperkalaemia‐induced loss of twitch force in rat slow‐twitch muscle MG Van Emst, S Klarenbeek, A Schot, JJ Plomp, A Doornenbal, ... The Journal of Physiology 561 (1), 169-181, 2004 | 18 | 2004 |
| Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation M Van Miltenburg, MJ Van Nimwegen, I Tijdens, R Lalai, R Kuiper, ... British journal of cancer 110 (11), 2747-2755, 2014 | 17 | 2014 |
| p120-catenin is critical for the development of invasive lobular carcinoma in mice M Tenhagen, S Klarenbeek, TM Braumuller, I Hofmann, P van der Groep, ... Journal of Mammary Gland Biology and Neoplasia 21, 81-88, 2016 | 15 | 2016 |
