Accurate classification of BRCA1 variants with saturation genome editing GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith, M Gasperini, ... Nature 562 (7726), 217-222, 2018 | 776 | 2018 |
Network modeling links breast cancer susceptibility and centrosome dysfunction MA Pujana, JDJ Han, LM Starita, KN Stevens, M Tewari, JS Ahn, ... Nature genetics 39 (11), 1338-1349, 2007 | 731 | 2007 |
Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation DL Swaney, P Beltrao, L Starita, A Guo, J Rush, S Fields, NJ Krogan, ... Nature methods 10 (7), 676-682, 2013 | 711 | 2013 |
Recommendations for application of the functional evidence PS3/BS3 criterion using the ACMG/AMP sequence variant interpretation framework SE Brnich, AN Abou Tayoun, FJ Couch, GR Cutting, MS Greenblatt, ... Genome medicine 12, 1-12, 2020 | 453 | 2020 |
Multiplex assessment of protein variant abundance by massively parallel sequencing KA Matreyek, LM Starita, JJ Stephany, B Martin, MA Chiasson, VE Gray, ... Nature genetics 50 (6), 874-882, 2018 | 418 | 2018 |
BRCA1-dependent ubiquitination of γ-tubulin regulates centrosome number LM Starita, Y Machida, S Sankaran, JE Elias, K Griffin, BP Schlegel, ... Molecular and cellular biology 24 (19), 8457-8466, 2004 | 411 | 2004 |
Variant interpretation: functional assays to the rescue LM Starita, N Ahituv, MJ Dunham, JO Kitzman, FP Roth, G Seelig, ... The American Journal of Human Genetics 101 (3), 315-325, 2017 | 373 | 2017 |
Massively parallel functional analysis of BRCA1 RING domain variants LM Starita, DL Young, M Islam, JO Kitzman, J Gullingsrud, RJ Hause, ... Genetics 200 (2), 413-422, 2015 | 345 | 2015 |
Cryptic transmission of SARS-CoV-2 in Washington state T Bedford, AL Greninger, P Roychoudhury, LM Starita, M Famulare, ... Science 370 (6516), 571-575, 2020 | 310 | 2020 |
The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair LM Starita, JD Parvin Current opinion in cell biology 15 (3), 345-350, 2003 | 301 | 2003 |
Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California X Deng, W Gu, S Federman, L Du Plessis, OG Pybus, NR Faria, C Wang, ... Science 369 (6503), 582-587, 2020 | 276 | 2020 |
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis LM Starita, JN Pruneda, RS Lo, DM Fowler, HJ Kim, JB Hiatt, J Shendure, ... Proceedings of the National Academy of Sciences 110 (14), E1263-E1272, 2013 | 228 | 2013 |
On the design of CRISPR-based single-cell molecular screens AJ Hill, JL McFaline-Figueroa, LM Starita, MJ Gasperini, KA Matreyek, ... Nature methods 15 (4), 271-274, 2018 | 222 | 2018 |
MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect D Esposito, J Weile, J Shendure, LM Starita, AT Papenfuss, FP Roth, ... Genome biology 20, 1-11, 2019 | 211 | 2019 |
Massively parallel single-amino-acid mutagenesis JO Kitzman, LM Starita, RS Lo, S Fields, J Shendure Nature methods 12 (3), 203-206, 2015 | 206 | 2015 |
Evidence for limited early spread of COVID-19 within the United States, January–February 2020 MA Jorden, SL Rudman, E Villarino, S Hoferka, MT Patel, K Bemis, ... Morbidity and Mortality Weekly Report 69 (22), 680-684, 2020 | 191 | 2020 |
BRCA1/BARD1 Ubiquitinate Phosphorylated RNA Polymerase II LM Starita, AA Horwitz, MC Keogh, C Ishioka, JD Parvin, N Chiba Journal of Biological Chemistry 280 (26), 24498-24505, 2005 | 189 | 2005 |
The power of multiplexed functional analysis of genetic variants M Gasperini, L Starita, J Shendure Nature protocols 11 (10), 1782-1787, 2016 | 173 | 2016 |
Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination S Sankaran, LM Starita, AC Groen, MJ Ko, JD Parvin Molecular and cellular biology 25 (19), 8656-8668, 2005 | 154 | 2005 |
Comparison of symptoms and RNA levels in children and adults with SARS-CoV-2 infection in the community setting E Chung, EJ Chow, NC Wilcox, R Burstein, E Brandstetter, PD Han, K Fay, ... JAMA pediatrics 175 (10), e212025-e212025, 2021 | 129 | 2021 |