Serine/threonine protein kinases and apoptosis TG Cross, D Scheel-Toellner, NV Henriquez, E Deacon, M Salmon, ... Experimental cell research 256 (1), 34-41, 2000 | 861 | 2000 |
Aging of the innate immune system AC Shaw, S Joshi, H Greenwood, A Panda, JM Lord Current opinion in immunology 22 (4), 507-513, 2010 | 695 | 2010 |
Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation CD Buckley, D Pilling, JM Lord, AN Akbar, D Scheel-Toellner, M Salmon Trends in immunology 22 (4), 199-204, 2001 | 680 | 2001 |
The systemic immune response to trauma: an overview of pathophysiology and treatment JM Lord, MJ Midwinter, YF Chen, A Belli, K Brohi, EJ Kovacs, ... The Lancet 384 (9952), 1455-1465, 2014 | 623 | 2014 |
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin K Raza, F Falciani, SJ Curnow, EJ Ross, CY Lee, AN Akbar, JM Lord, ... Arthritis research & therapy 7, 1-12, 2005 | 606 | 2005 |
RGD peptides induce apoptosis by direct caspase-3 activation CD Buckley, D Pilling, NV Henriquez, G Parsonage, K Threlfall, ... Nature 397 (6719), 534-539, 1999 | 582 | 1999 |
Human innate immunosenescence: causes and consequences for immunity in old age A Panda, A Arjona, E Sapey, F Bai, E Fikrig, RR Montgomery, JM Lord, ... Trends in immunology 30 (7), 325-333, 2009 | 513 | 2009 |
Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans SK Butcher, H Chahal, L Nayak, A Sinclair, NV Henriquez, E Sapey, ... Journal of leukocyte biology 70 (6), 881-886, 2001 | 448 | 2001 |
Frailty and sarcopenia: the potential role of an aged immune system D Wilson, T Jackson, E Sapey, JM Lord Ageing research reviews 36, 1-10, 2017 | 421 | 2017 |
Persistent induction of the chemokine receptor CXCR4 by TGF-β1 on synovial T cells contributes to their accumulation within the rheumatoid synovium CD Buckley, N Amft, PF Bradfield, D Pilling, E Ross, ... The Journal of Immunology 165 (6), 3423-3429, 2000 | 393 | 2000 |
Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence E Sapey, H Greenwood, G Walton, E Mann, A Love, N Aaronson, ... Blood, The Journal of the American Society of Hematology 123 (2), 239-248, 2014 | 313 | 2014 |
PKC-δ is an apoptotic lamin kinase T Cross, G Griffiths, E Deacon, R Sallis, M Gough, D Watters, JM Lord Oncogene 19 (19), 2331-2337, 2000 | 278 | 2000 |
Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity? NA Duggal, G Niemiro, SDR Harridge, RJ Simpson, JM Lord Nature Reviews Immunology 19 (9), 563-572, 2019 | 275 | 2019 |
Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals J Hazeldine, P Harris, IL Chapple, M Grant, H Greenwood, A Livesey, ... Aging cell 13 (4), 690-698, 2014 | 260 | 2014 |
The impact of ageing on natural killer cell function and potential consequences for health in older adults J Hazeldine, JM Lord Ageing research reviews 12 (4), 1069-1078, 2013 | 240 | 2013 |
Spontaneous neutrophil apoptosis involves caspase 3-mediated activation of protein kinase C-δ J Pongracz, P Webb, K Wang, E Deacon, OJ Lunn, JM Lord Journal of Biological Chemistry 274 (52), 37329-37334, 1999 | 235 | 1999 |
Neutrophil ageing and immunesenescence JM Lord, S Butcher, V Killampali, D Lascelles, M Salmon Mechanisms of ageing and development 122 (14), 1521-1535, 2001 | 232 | 2001 |
Diacylglycerol and phosphatidate generated by phospholipases C and D, respectively, have distinct fatty acid compositions and functions: phospholipase D-derived diacylglycerol … TR Pettitt, A Martin, T Horton, C Liossis, JM Lord, MJO Wakelam Journal of Biological Chemistry 272 (28), 17354-17359, 1997 | 230 | 1997 |
The age‐related increase in low‐grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection DB Bartlett, CM Firth, AC Phillips, P Moss, D Baylis, H Syddall, AA Sayer, ... Aging cell 11 (5), 912-915, 2012 | 222 | 2012 |
Immune-endocrine biomarkers as predictors of frailty and mortality: a 10-year longitudinal study in community-dwelling older people D Baylis, DB Bartlett, HE Syddall, G Ntani, CR Gale, C Cooper, JM Lord, ... Age 35, 963-971, 2013 | 221 | 2013 |