Michelle Arkin
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Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
MR Arkin, JA Wells
Nature reviews Drug discovery 3 (4), 301-317, 2004
Long-range photoinduced electron transfer through a DNA helix
CJ Murphy, MR Arkin, Y Jenkins, ND Ghatlia, SH Bossmann, NJ Turro, ...
Science 262 (5136), 1025-1029, 1993
Small-molecule inhibitors of protein-protein interactions: progressing toward the reality
MR Arkin, Y Tang, JA Wells
Chemistry & biology 21 (9), 1102-1114, 2014
Pharmacological brake-release of mRNA translation enhances cognitive memory
C Sidrauski, D Acosta-Alvear, A Khoutorsky, P Vedantham, BR Hearn, ...
elife 2, e00498, 2013
Rates of DNA-mediated electron transfer between metallointercalators
MR Arkin, EDA Stemp, RE Holmlin, JK Barton, A Hörmann, EJC Olson, ...
Science 273 (5274), 475-480, 1996
Binding of small molecules to an adaptive protein–protein interface
MR Arkin, M Randal, WL DeLano, J Hyde, TN Luong, JD Oslob, ...
Proceedings of the National Academy of Sciences 100 (4), 1603-1608, 2003
First observation of the key intermediate in the “light-switch” mechanism of [Ru (phen) 2dppz] 2+
EJC Olson, D Hu, A Hörmann, AM Jonkman, MR Arkin, EDA Stemp, ...
Journal of the American Chemical Society 119 (47), 11458-11467, 1997
2.3 Ĺ resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition
S Banerjee, A Bartesaghi, A Merk, P Rao, SL Bulfer, Y Yan, N Green, ...
Science 351 (6275), 871-875, 2016
A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target
A Debnath, D Parsonage, RM Andrade, C He, ER Cobo, K Hirata, S Chen, ...
Nature medicine 18 (6), 956-960, 2012
Oxidation of guanine in DNA by Ru (phen) 2 (dppz) 3+ using the flash-quench technique
EDA Stemp, MR Arkin, JK Barton
Journal of the American Chemical Society 119 (12), 2921-2925, 1997
Discovery of a potent small molecule IL-2 inhibitor through fragment assembly
AC Braisted, JD Oslob, WL Delano, J Hyde, RS McDowell, N Waal, C Yu, ...
Journal of the American Chemical Society 125 (13), 3714-3715, 2003
USP7 small-molecule inhibitors interfere with ubiquitin binding
L Kategaya, P Di Lello, L Rougé, R Pastor, KR Clark, J Drummond, ...
Nature 550 (7677), 534-538, 2017
Fast photoinduced electron transfer through DNA intercalation.
CJ Murphy, MR Arkin, ND Ghatlia, S Bossmann, NJ Turro, JK Barton
Proceedings of the National Academy of Sciences 91 (12), 5315-5319, 1994
Long-range oxidation of guanine by Ru (III) in duplex DNA
MR Arkin, EDA Stemp, SC Pulver, JK Barton
Chemistry & Biology 4 (5), 389-400, 1997
Assay guidance manual
GS Sittampalam, NP Coussens, H Nelson, M Arkin, D Auld, C Austin, ...
Eli Lilly & Company and the National Center for Advancing Translational Sciences, 2004
Protein–protein interactions and cancer: small molecules going in for the kill
M Arkin
Current opinion in chemical biology 9 (3), 317-324, 2005
A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit
G De Muylder, KKH Ang, S Chen, MR Arkin, JC Engel, JH McKerrow
PLoS neglected tropical diseases 5 (7), e1253, 2011
Two approaches to discovering and developing new drugs for Chagas disease
JH McKerrow, PS Doyle, JC Engel, LM Podust, SA Robertson, R Ferreira, ...
Memórias do Instituto Oswaldo Cruz 104, 263-269, 2009
Screening for noise in gene expression identifies drug synergies
RD Dar, NN Hosmane, MR Arkin, RF Siliciano, LS Weinberger
Science 344 (6190), 1392-1396, 2014
Luminescence quenching in supramolecular systems: a comparison of DNA-and SDS micelle-mediated photoinduced electron transfer between metal complexes
MR Arkin, EDA Stemp, C Turro, NJ Turro, JK Barton
Journal of the American Chemical Society 118 (9), 2267-2274, 1996
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