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Patrick Tan
Patrick Tan
Duke-NUS Medical School
Verified email at duke-nus.edu.sg
Title
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Cited by
Year
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
R Cristescu, J Lee, M Nebozhyn, KM Kim, JC Ting, SS Wong, J Liu, ...
Nature medicine 21 (5), 449-456, 2015
18152015
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1650*2020
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
S Varambally, Q Cao, RS Mani, S Shankar, X Wang, B Ateeq, B Laxman, ...
science 322 (5908), 1695-1699, 2008
13422008
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
J Tan, X Yang, L Zhuang, X Jiang, W Chen, PL Lee, RKM Karuturi, ...
Genes & development 21 (9), 1050-1063, 2007
10272007
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma
A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ...
Cancer discovery 7 (10), 1116-1135, 2017
7152017
A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets
N Deng, LK Goh, H Wang, K Das, J Tao, IB Tan, S Zhang, M Lee, J Wu, ...
Gut 61 (5), 673-684, 2012
7052012
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
ZJ Zang, I Cutcutache, SL Poon, SL Zhang, JR McPherson, J Tao, ...
Nature genetics 44 (5), 570-574, 2012
6882012
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ...
Nature medicine 18 (4), 521-528, 2012
6612012
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
N Palanisamy, B Ateeq, S Kalyana-Sundaram, D Pflueger, ...
Nature medicine 16 (7), 793-798, 2010
5492010
" Fluorescent timer": protein that changes color with time
A Terskikh, A Fradkov, G Ermakova, A Zaraisky, P Tan, AV Kajava, X Zhao, ...
Science 290 (5496), 1585-1588, 2000
5452000
Exome sequencing of liver fluke–associated cholangiocarcinoma
CK Ong, C Subimerb, C Pairojkul, S Wongkham, I Cutcutache, W Yu, ...
Nature genetics 44 (6), 690-693, 2012
5052012
Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target
Y Wang, ATC Lee, JZI Ma, J Wang, J Ren, Y Yang, E Tantoso, KB Li, ...
Journal of Biological Chemistry 283 (19), 13205-13215, 2008
4992008
Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers
W Chan-On, ML Nairismägi, CK Ong, WK Lim, S Dima, C Pairojkul, ...
Nature genetics 45 (12), 1474-1478, 2013
4862013
Genetics and molecular pathogenesis of gastric adenocarcinoma
P Tan, KG Yeoh
Gastroenterology 149 (5), 1153-1162. e3, 2015
4582015
Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil
Z Lei, IB Tan, K Das, N Deng, H Zouridis, S Pattison, C Chua, Z Feng, ...
Gastroenterology 145 (3), 554-565, 2013
4542013
Oncogenic pathway combinations predict clinical prognosis in gastric cancer
CH Ooi, T Ivanova, J Wu, M Lee, IB Tan, J Tao, L Ward, JH Koo, ...
PLoS genetics 5 (10), e1000676, 2009
4152009
Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy
IB Tan, T Ivanova, KH Lim, CW Ong, N Deng, J Lee, SH Tan, J Wu, ...
Gastroenterology 141 (2), 476-485. e11, 2011
4052011
Paradoxical relationship between chromosomal instability and survival outcome in cancer
NJ Birkbak, AC Eklund, Q Li, SE McClelland, D Endesfelder, P Tan, ...
Cancer research 71 (10), 3447-3452, 2011
3952011
Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes
MK Keck, Z Zuo, A Khattri, TP Stricker, CD Brown, M Imanguli, D Rieke, ...
Clinical cancer research 21 (4), 870-881, 2015
3762015
Genetic algorithms applied to multi-class prediction for the analysis of gene expression data
CH Ooi, P Tan
Bioinformatics 19 (1), 37-44, 2003
3532003
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Articles 1–20