Diurnal variation in serum levels of cartilage oligomeric matrix protein in patients with knee osteoarthritis or rheumatoid arthritis MLE Andersson, IF Petersson, KE Karlsson, EN Jonsson, B Månsson, ... Annals of the rheumatic diseases 65 (11), 1490-1494, 2006 | 91 | 2006 |
Advanced methods for dose and regimen finding during drug development: summary of the EMA/EFPIA workshop on dose finding (London 4–5 December 2014) FT Musuamba, E Manolis, N Holford, SYA Cheung, LE Friberg, ... CPT: pharmacometrics & systems pharmacology 6 (7), 418-429, 2017 | 61 | 2017 |
Comparisons of analysis methods for proof‐of‐concept trials KE Karlsson, C Vong, M Bergstrand, EN Jonsson, MO Karlsson CPT: pharmacometrics & systems pharmacology 2 (1), 1-8, 2013 | 57 | 2013 |
Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility FT Musuamba, I Skottheim Rusten, R Lesage, G Russo, R Bursi, L Emili, ... CPT: Pharmacometrics & Systems Pharmacology 10 (8), 804-825, 2021 | 50 | 2021 |
Performance of three estimation methods in repeated time-to-event modeling KE Karlsson, EL Plan, MO Karlsson The AAPS journal 13, 83-91, 2011 | 42 | 2011 |
Approaches to simultaneous analysis of frequency and severity of symptoms EL Plan, KE Karlsson, MO Karlsson Clinical Pharmacology & Therapeutics 88 (2), 255-259, 2010 | 30 | 2010 |
Population pharmacokinetics of edoxaban in patients with non-valvular atrial fibrillation in the ENGAGE AF-TIMI 48 study, a phase III clinical trial EHJ Krekels, R Niebecker, MO Karlsson, R Miller, T Shimizu, KE Karlsson, ... Clinical Pharmacokinetics 55, 1079-1090, 2016 | 28 | 2016 |
Randomized exposure‐controlled trials; impact of randomization and analysis strategies KE Karlsson, A Grahnén, MO Karlsson, EN Jonsson British journal of clinical pharmacology 64 (3), 266-277, 2007 | 22 | 2007 |
Commentary on the EMA R eflection P aper on the use of extrapolation in the development of medicines for paediatrics C Ollivier, A Thomson, E Manolis, K Blake, KE Karlsson, CAJ Knibbe, ... British Journal of Clinical Pharmacology 85 (4), 659-668, 2019 | 21 | 2019 |
Verifying and validating quantitative systems pharmacology and in silico models in drug development: current needs, gaps, and challenges FT Musuamba, R Bursi, E Manolis, K Karlsson, A Kulesza, E Courcelles, ... CPT: Pharmacometrics & Systems Pharmacology 9 (4), 195, 2020 | 19 | 2020 |
Commentary on the MID3 good practices paper E Manolis, J Brogren, S Cole, JL Hay, A Nordmark, KE Karlsson, F Lentz, ... CPT: Pharmacometrics & Systems Pharmacology 6 (7), 416-417, 2017 | 16 | 2017 |
Environmental risk assessment of sediments deposited in stormwater treatment facilities: trace metal fractionation and its implication for sediment management K Karlsson, GT Blecken, B Öhlander, M Viklander Journal of Environmental Engineering 142 (11), 04016057, 2016 | 14 | 2016 |
Edoxaban Exposure‐Response Analysis and Clinical Utility Index Assessment in Patients With Symptomatic Deep‐Vein Thrombosis or Pulmonary Embolism J Nyberg, KE Karlsson, S Jönsson, OQP Yin, R Miller, MO Karlsson, ... CPT: Pharmacometrics & Systems Pharmacology 5 (4), 222-232, 2016 | 12 | 2016 |
Modeling disease progression in acute stroke using clinical assessment scales KE Karlsson, JJ Wilkins, F Jonsson, PH Zingmark, MO Karlsson, ... The AAPS journal 12, 683-691, 2010 | 11 | 2010 |
Simulating large time-to-event trials in NONMEM J Nyberg, KE Karlsson, S Jönsson, USH Simonsson, MO Karlsson, ... Page 23, 3166, 2014 | 10 | 2014 |
Benefits of pharmacometric model-based design and analysis of clinical trials KE Karlsson Acta Universitatis Upsaliensis, 2010 | 10 | 2010 |
Fältarbetsinstruktion för Skogsfakultetens beståndsbehandlingsförsök K Karlsson Swedish University of Agricultural Sciences, 2003 | 9 | 2003 |
The European medicines agency experience with pediatric dose selection E Manolis, FT Musuamba, KE Karlsson The Journal of Clinical Pharmacology 61, S22-S27, 2021 | 7 | 2021 |
Motivation in the Gig Economy: A Case Study of Gig Workers in the IT and Business Consulting Industry K Karlsson, J Wranne | 6 | 2019 |
A future legal coordinated cadastre for Sweden K Karlsson International Symposium and Exhibition on Geoinformation, 2005 | 5 | 2005 |