Simone Furini
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Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
Burden-driven feedback control of gene expression
F Ceroni, A Boo, S Furini, TE Gorochowski, O Borkowski, YN Ladak, ...
Nature methods 15 (5), 387-393, 2018
ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population
E Benetti, R Tita, O Spiga, A Ciolfi, G Birolo, A Bruselles, G Doddato, ...
European Journal of Human Genetics 28 (11), 1602-1614, 2020
Whole-genome sequencing reveals host factors underlying critical COVID-19
A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ...
Nature 607 (7917), 97-103, 2022
Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study
C Fallerini, S Daga, S Mantovani, E Benetti, N Picchiotti, D Francisci, ...
elife 10, e67569, 2021
Atypical mechanism of conduction in potassium channels
S Furini, C Domene
Proceedings of the National Academy of Sciences 106 (38), 16074-16077, 2009
On conduction in a bacterial sodium channel
S Furini, C Domene
PLoS computational biology 8 (4), e1002476, 2012
Revealing the complexity of a monogenic disease: Rett syndrome exome sequencing
E Grillo, C Lo Rizzo, L Bianciardi, V Bizzarri, M Baldassarri, O Spiga, ...
PloS one 8 (2), e56599, 2013
DNA-recognition process described by MD simulations of the lactose repressor protein on a specific and a non-specific DNA sequence
S Furini, P Barbini, C Domene
Nucleic acids research 41 (7), 3963-3972, 2013
Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males
M Baldassarri, N Picchiotti, F Fava, C Fallerini, E Benetti, S Daga, ...
EBioMedicine 65, 2021
K+ and Na+ conduction in selective and nonselective ion channels via molecular dynamics simulations
S Furini, C Domene
Biophysical journal 105 (8), 1737-1745, 2013
Bias-exchange metadynamics simulations: an efficient strategy for the analysis of conduction and selectivity in ion channels
C Domene, P Barbini, S Furini
Journal of Chemical Theory and Computation 11 (4), 1896-1906, 2015
Protective Role of a TMPRSS2 Variant on Severe COVID-19 Outcome in Young Males and Elderly Women
M Monticelli, B Hay Mele, E Benetti, C Fallerini, M Baldassarri, S Furini, ...
Genes 12 (4), 596, 2021
Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients
S Mantovani, S Daga, C Fallerini, M Baldassarri, E Benetti, N Picchiotti, ...
Genes & Immunity 23 (1), 51-56, 2022
Dynamics, energetics, and selectivity of the low-K+ KcsA channel structure
C Domene, S Furini
Journal of molecular biology 389 (3), 637-645, 2009
The role of conformation in ion permeation in a K+ channel
C Domene, S Vemparala, S Furini, K Sharp, ML Klein
Journal of the American Chemical Society 130 (11), 3389-3398, 2008
Application of the Poisson-Nernst-Planck theory with space-dependent diffusion coefficients to KcsA
S Furini, F Zerbetto, S Cavalcanti
Biophysical journal 91 (9), 3162-3169, 2006
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome
E Landucci, M Brindisi, L Bianciardi, LM Catania, S Daga, S Croci, ...
Experimental cell research 368 (2), 225-235, 2018
Permeation and dynamics of an open-activated TRPV1 channel
L Darré, S Furini, C Domene
Journal of molecular biology 427 (2), 537-549, 2015
Three-dimensional Brownian dynamics simulator for the study of ion permeation through membrane pores
C Berti, S Furini, D Gillespie, D Boda, RS Eisenberg, E Sangiorgi, ...
Journal of chemical theory and computation 10 (8), 2911-2926, 2014
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