Catalytic in vivo protein knockdown by small-molecule PROTACs DP Bondeson, A Mares, IED Smith, E Ko, S Campos, AH Miah, ... Nature chemical biology 11 (8), 611-617, 2015 | 1209 | 2015 |
Systematic analysis of protein turnover in primary cells T Mathieson, H Franken, J Kosinski, N Kurzawa, N Zinn, G Sweetman, ... Nature communications 9 (1), 689, 2018 | 352 | 2018 |
Measuring and managing ratio compression for accurate iTRAQ/TMT quantification MM Savitski, T Mathieson, N Zinn, G Sweetman, C Doce, I Becher, ... Journal of proteome research 12 (8), 3586-3598, 2013 | 302 | 2013 |
De novo sequencing of peptides by MS/MS J Seidler, N Zinn, ME Boehm, WD Lehmann Proteomics 10 (4), 634-649, 2010 | 287 | 2010 |
Biological plasticity rescues target activity in CRISPR knock outs AH Smits, F Ziebell, G Joberty, N Zinn, WF Mueller, S Clauder-Münster, ... Nature methods 16 (11), 1087-1093, 2019 | 231 | 2019 |
Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis MM Savitski, N Zinn, M Faelth-Savitski, D Poeckel, S Gade, I Becher, ... Cell 173 (1), 260-274. e25, 2018 | 214 | 2018 |
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis HV Woodcock, JD Eley, D Guillotin, M Platé, CB Nanthakumar, M Martufi, ... Nature communications 10 (1), 6, 2019 | 179 | 2019 |
Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson’s disease-related toxicity in human neurons N Ramsden, J Perrin, Z Ren, BD Lee, N Zinn, VL Dawson, D Tam, M Bova, ... ACS chemical biology 6 (10), 1021-1028, 2011 | 177 | 2011 |
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2 A Mares, AH Miah, IED Smith, M Rackham, AR Thawani, J Cryan, ... Communications biology 3 (1), 140, 2020 | 174 | 2020 |
Delayed fragmentation and optimized isolation width settings for improvement of protein identification and accuracy of isobaric mass tag quantification on Orbitrap-type mass … MM Savitski, G Sweetman, M Askenazi, JA Marto, M Lang, N Zinn, ... Analytical chemistry 83 (23), 8959-8967, 2011 | 122 | 2011 |
Discovery and characterisation of highly cooperative FAK‐degrading PROTACs RP Law, J Nunes, C Chung, M Bantscheff, K Buda, H Dai, JP Evans, ... Angewandte Chemie International Edition 60 (43), 23327-23334, 2021 | 81 | 2021 |
Discovery of GSK8612, a highly selective and potent TBK1 inhibitor DW Thomson, D Poeckel, N Zinn, C Rau, K Strohmer, AJ Wagner, ... ACS medicinal chemistry letters 10 (5), 780-785, 2019 | 74 | 2019 |
Protein labelling with mercury tags: fundamental studies on ovalbumin derivatised with p-hydroxymercuribenzoic acid (pHMB) DJ Kutscher, ME del Castillo Busto, N Zinn, A Sanz-Medel, J Bettmer Journal of Analytical Atomic Spectrometry 23 (10), 1359-1364, 2008 | 60 | 2008 |
μLC coupled to ICP–SFMS with post-column isotope dilution analysis of sulfur for absolute protein quantification N Zinn, R Krüger, P Leonhard, J Bettmer Analytical and bioanalytical chemistry 391, 537-543, 2008 | 52 | 2008 |
Improved proteomics-based drug mechanism-of-action studies using 16-plex isobaric mass tags N Zinn, T Werner, C Doce, T Mathieson, C Boecker, G Sweetman, ... Journal of Proteome Research 20 (3), 1792-1801, 2021 | 50 | 2021 |
Recombinant isotope labeled and selenium quantified proteins for absolute protein quantification N Zinn, D Winter, WD Lehmann Analytical chemistry 82 (6), 2334-2340, 2010 | 44 | 2010 |
Phosphorus-based absolutely quantified standard peptides for quantitative proteomics N Zinn, B Hahn, R Pipkorn, D Schwarzer, WD Lehmann Journal of Proteome Research 8 (10), 4870-4875, 2009 | 44 | 2009 |
Gel Electrophoresis Coupled to Inductively Coupled Plasma− Mass Spectrometry Using Species-Specific Isotope Dilution for Iodide and Iodate Determination in Aerosols W Brüchert, A Helfrich, N Zinn, T Klimach, M Breckheimer, H Chen, S Lai, ... Analytical chemistry 79 (4), 1714-1719, 2007 | 39 | 2007 |
Metal ion-mobilizing additives for comprehensive detection of femtomole amounts of phosphopeptides by reversed phase LC-MS J Seidler, N Zinn, E Haaf, ME Boehm, D Winter, A Schlosser, ... Amino Acids 41, 311-320, 2011 | 38 | 2011 |
An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices MM Khan, D Poeckel, A Halavatyi, J Zukowska-Kasprzyk, F Stein, ... European Respiratory Journal 58 (1), 2021 | 33 | 2021 |