Jessica C. S. Brown
Jessica C. S. Brown
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A heritable switch in carbon source utilization driven by an unusual yeast prion
JCS Brown, S Lindquist
Genes & development 23 (19), 2320-2332, 2009
A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice
JLR Tyson R. Chiaro, Ray Soto, W. Zac Stephens, Jason L. Kubinak, Charisse ...
Science Translational Medicine 9 (380), eaaf9044, 2017
Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism
DF Jarosz, J Brown, GA Walker, MS Datta, WL Ung, AK Lancaster, ...
Cell 158 (5), 1083-1093, 2014
An Evolutionarily Conserved Prion-like Element Converts Wild Fungi from Metabolic Specialists to Generalists
DF Jarosz, AK Lancaster, J Brown, S Lindquist
Cell 158 (5), 1072-1082, 2014
Saccharomyces cerevisiae DNA polymerase ε and polymerase σ interact physically and functionally, suggesting a role for polymerase ε in sister chromatid cohesion
S Edwards, CM Li, DL Levy, J Brown, PM Snow, JL Campbell
Molecular and cellular biology 23 (8), 2733-2748, 2003
Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with Fluconazole In Vivo
A Butts, K Koselny, Y Chabrier-Roselló, CP Semighini, JCS Brown, ...
MBio 5 (1), e00765-13, 2014
A Major Role for Capsule-Independent Phagocytosis-Inhibitory Mechanisms in Mammalian Infection by Cryptococcus neoformans
CD Chun, J Brown, HD Madhani
Cell host & microbe 9 (3), 243-251, 2011
Unraveling the Biology of a Fungal Meningitis Pathogen Using Chemical Genetics
JCS Brown, J Nelson, B VanderSluis, R Deshpande, A Butts, S Kagan, ...
Cell 159 (5), 1168-1187, 2014
High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance
MA Wambaugh, VPS Shakya, AJ Lewis, MA Mulvey, JCS Brown
PLoS Biology 15 (6), e2001644, 2017
Phytotherapy as an alternative to conventional antimicrobials: combating microbial resistance
SCMT Enioutina EY, Teng L, Fateeva TV, Brown JCS, Job KM, Bortnikova VV ...
Expert Rev Clin Pharmacol, doi: 10.1080/17512433.2017.1371591, 2017
Mechanisms of Pulmonary Escape and Dissemination by Cryptococcus neoformans
ST Denham, J Brown
Journal of Fungi 4 (1), 25, 2018
Regulated release of cryptococcal polysaccharide drives virulence and suppresses immune cell infiltration into the central nervous system
ST Denham, S Verma, RC Reynolds, CL Worne, JM Daugherty, TE Lane, ...
Infection and immunity 86 (3), e00662-17, 2018
Synergistic and antagonistic drug interactions in the treatment of systemic fungal infections
MA Wambaugh, ST Denham, M Ayala, B Brammer, MA Stonhill, ...
Elife 9, e54160, 2020
Cisplatin DNA cross-links do not inhibit S-phase and cause only a G2/M arrest in Saccharomyces cerevisiae
KF Grossmann, JC Brown, RE Moses
Mutation Research/DNA Repair 434 (1), 29-39, 1999
How environmental fungi cause a range of clinical outcomes in susceptible hosts
ST Denham, MA Wambaugh, JCS Brown
Journal of molecular biology 431 (16), 2982-3009, 2019
A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans
ST Denham, B Brammer, KY Chung, MA Wambaugh, JM Bednarek, ...
Cell Host & Microbe 30 (10), 1382-1400. e8, 2022
Approaching the functional annotation of fungal virulence factors using cross-species genetic interaction profiling
JCS Brown, HD Madhani
PLoS genetics 8 (12), e1003168, 2012
Biology and Function of Exo-Polysaccharides from Human Fungal Pathogens
KY Chung, JCS Brown
Current Clinical Microbiology Reports 7 (1), 1-11, 2020
High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
MA Wambaugh, JCS Brown
JoVE (Journal of Visualized Experiments), e57241, 2018
antifungal pipeline: build it strong; build it better!
JR Perfect, DJ Krysan, M Del Poeta, AM Selmecki, J Brown, LE Cowen
Frontiers in Cellular and Infection Microbiology 12, 881272, 2022
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