HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types A Zirkel, M Nikolic, K Sofiadis, JP Mallm, CA Brackley, H Gothe, ... Molecular cell 70 (4), 730-744. e6, 2018 | 182 | 2018 |
The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation M Kalwa, S Hänzelmann, S Otto, CC Kuo, J Franzen, S Joussen, ... Nucleic acids research 44 (22), 10631-10643, 2016 | 157 | 2016 |
Senescence‐associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells J Franzen, A Zirkel, J Blake, B Rath, V Benes, A Papantonis, W Wagner Aging cell 16 (1), 183-191, 2017 | 85 | 2017 |
Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells E Fernandez-Rebollo, B Mentrup, R Ebert, J Franzen, G Abagnale, ... Scientific reports 7 (1), 5132, 2017 | 84 | 2017 |
Senescence-associated metabolomic phenotype in primary and iPSC-derived mesenchymal stromal cells E Fernandez-Rebollo, J Franzen, R Goetzke, J Hollmann, A Ostrowska, ... Stem cell reports 14 (2), 201-209, 2020 | 68 | 2020 |
Effects of senolytic drugs on human mesenchymal stromal cells C Grezella, E Fernandez-Rebollo, J Franzen, MS Ventura Ferreira, ... Stem cell research & therapy 9, 1-6, 2018 | 68 | 2018 |
New targeted approaches for epigenetic age predictions Y Han, J Franzen, T Stiehl, M Gobs, CC Kuo, M Nikolić, J Hapala, ... BMC biology 18, 1-15, 2020 | 64 | 2020 |
Epigenetic age-predictor for mice based on three CpG sites Y Han, M Eipel, J Franzen, V Sakk, B Dethmers-Ausema, L Yndriago, ... Elife 7, e37462, 2018 | 64 | 2018 |
Epigenetic classification of human mesenchymal stromal cells DC de Almeida, MRP Ferreira, J Franzen, CI Weidner, J Frobel, M Zenke, ... Stem cell reports 6 (2), 168-175, 2016 | 59 | 2016 |
yylncT defines a class of divergently transcribed lncRNAs and safeguards the T-mediated mesodermal commitment of human PSCs S Frank, G Ahuja, D Bartsch, N Russ, W Yao, JCC Kuo, JP Derks, ... Cell stem cell 24 (2), 318-327. e8, 2019 | 55 | 2019 |
DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift J Franzen, T Georgomanolis, A Selich, CC Kuo, R Stöger, L Brant, ... Communications biology 4 (1), 598, 2021 | 38 | 2021 |
Does soft really matter? Differentiation of induced pluripotent stem cells into mesenchymal stromal cells is not influenced by soft hydrogels R Goetzke, J Franzen, A Ostrowska, M Vogt, A Blaeser, G Klein, B Rath, ... Biomaterials 156, 147-158, 2018 | 34 | 2018 |
Epigenetic clocks are not accelerated in COVID-19 patients J Franzen, S Nüchtern, V Tharmapalan, M Vieri, M Nikolić, Y Han, ... International Journal of Molecular Sciences 22 (17), 9306, 2021 | 33 | 2021 |
PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation O Cypris, M Eipel, J Franzen, C Rösseler, V Tharmapalan, CC Kuo, ... Clinical epigenetics 12, 1-14, 2020 | 27 | 2020 |
Differentiation of induced pluripotent stem cells towards mesenchymal stromal cells is hampered by culture in 3D hydrogels R Goetzke, H Keijdener, J Franzen, A Ostrowska, S Nüchtern, P Mela, ... Scientific Reports 9 (1), 15578, 2019 | 26 | 2019 |
Targeted methods for epigenetic age predictions in mice Y Han, M Nikolić, M Gobs, J Franzen, G de Haan, H Geiger, W Wagner Scientific reports 10 (1), 22439, 2020 | 20 | 2020 |
Investigation of measurable residual disease in acute myeloid leukemia by DNA methylation patterns T Božić, CC Kuo, J Hapala, J Franzen, M Eipel, U Platzbecker, ... Leukemia 36 (1), 80-89, 2022 | 18 | 2022 |
Genetic barcoding reveals clonal dominance in iPSC-derived mesenchymal stromal cells J Hollmann, J Brecht, R Goetzke, J Franzen, A Selich, M Schmidt, M Eipel, ... Stem cell research & therapy 11, 1-13, 2020 | 17 | 2020 |
Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells O Cypris, J Frobel, S Rai, J Franzen, S Sontag, R Goetzke, ... Clinical Epigenetics 11, 1-11, 2019 | 14 | 2019 |
Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice J Frobel, S Rahmig, J Franzen, C Waskow, W Wagner Clinical Epigenetics 10, 1-7, 2018 | 14 | 2018 |