| LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ... Cell metabolism 29 (4), 871-885. e5, 2019 | 344 | 2019 |
| Aging of mice is associated with p16 (Ink4a)-and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells BM Hall, V Balan, AS Gleiberman, E Strom, P Krasnov, LP Virtuoso, ... Aging (Albany NY) 8 (7), 1294, 2016 | 343 | 2016 |
| p16 (Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli BM Hall, V Balan, AS Gleiberman, E Strom, P Krasnov, LP Virtuoso, ... Aging (Albany NY) 9 (8), 1867, 2017 | 289 | 2017 |
| p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs KI Leonova, L Brodsky, B Lipchick, M Pal, L Novototskaya, AA Chenchik, ... Proceedings of the National Academy of Sciences 110 (1), E89-E98, 2013 | 265 | 2013 |
| Nrf2 amplifies oxidative stress via induction of Klf9 SN Zucker, EE Fink, A Bagati, S Mannava, A Bianchi-Smiraglia, ... Molecular cell 53 (6), 916-928, 2014 | 231 | 2014 |
| Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist LG Burdelya, CM Brackett, B Kojouharov, II Gitlin, KI Leonova, ... Proceedings of the National Academy of Sciences 110 (20), E1857-E1866, 2013 | 134 | 2013 |
| Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells A Tanne, LR Muniz, A Puzio-Kuter, KI Leonova, AV Gudkov, DT Ting, ... Proceedings of the National Academy of Sciences 112 (49), 15154-15159, 2015 | 81 | 2015 |
| Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice MP Antoch, M Wrobel, KK Kuropatwinski, I Gitlin, KI Leonova, I Toshkov, ... Aging (Albany NY) 9 (3), 615, 2017 | 72 | 2017 |
| A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice KI Leonova, J Shneyder, MP Antoch, IA Toshkov, LR Novototskaya, ... Cell Cycle 9 (7), 1434-1443, 2010 | 48 | 2010 |
| TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells K Leonova, A Safina, E Nesher, P Sandlesh, R Pratt, C Burkhart, ... Elife 7, e30842, 2018 | 42 | 2018 |
| Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma A Bianchi-Smiraglia, A Bagati, EE Fink, HC Affronti, BC Lipchick, ... The Journal of clinical investigation 128 (10), 4682-4696, 2018 | 40 | 2018 |
| Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion S Mannava, KC Moparthy, LJ Wheeler, KI Leonova, JA Wawrzyniak, ... Aging (Albany NY) 4 (12), 917, 2012 | 34 | 2012 |
| Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion S Mannava, KC Moparthy, LJ Wheeler, KI Leonova, JA Wawrzyniak, ... Aging (Albany NY) 4 (12), 917, 2012 | 34 | 2012 |
| Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma L Xiao, K Somers, J Murray, R Pandher, M Karsa, E Ronca, A Bongers, ... Clinical Cancer Research 27 (15), 4338-4352, 2021 | 17 | 2021 |
| Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors KA Novototskaya-Vlasova, NS Neznanov, I Molodtsov, BM Hall, ... Proceedings of the National Academy of Sciences 119 (49), e2213146119, 2022 | 5 | 2022 |
| Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice M Simon, MV Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, MD Cecco, ... bioRxiv, 460808, 2018 | 2 | 2018 |
| Comparison of cell response to chromatin and DNA damage A Luzhin, P Rajan, A Safina, K Leonova, A Stablewski, J Wang, ... Nucleic Acids Research 51 (21), 11836-11855, 2023 | 1 | 2023 |
| Cancer relevance of circulating antibodies against LINE-1 antigens in humans AV Vylegzhanina, IA Bespalov, KA Novototskaya-Vlasova, BM Hall, ... Cancer Research Communications 3 (11), 2256-2267, 2023 | | 2023 |
| Naturally occurring T-cell-mediated antitumor immune response to LINE-1 antigens in mice that can be enhanced by vaccination and TLR5 agonist KI Leonova, AS Gleiberman, V Jaravine, NH Trageser, ... | | 2023 |
| Dormant senescence-prone cells (DSPC): a lifetime memory about systemic genotoxic stress K Leonova, I Gitlin, A Gleiberman, I Toshkov, N Trageser, N Issaeva, ... | | 2022 |
